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The effects and mechanisms of the anti-COVID-19 traditional Chinese medicine, Dehydroandrographolide from Andrographis paniculata (Burm.f.) Wall, on acute lung injury by the inhibition of NLRP3-mediated pyroptosis

BACKGROUND: Dehydroandrographolide (Deh) from Andrographis paniculata (Burm.f.) Wall has strong anti-inflammatory and antioxidant activities. PURPOSE: To explore the role of Deh in acute lung injury (ALI) of coronavirus disease 19 (COVID-19) and its inflammatory molecular mechanism. METHODS: Liposac...

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Detalles Bibliográficos
Autores principales: Pu, Zhichen, Sui, Bangzhi, Wang, Xingwen, Wang, Wusuan, Li, Lingling, Xie, Haitang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier GmbH. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10060206/
https://www.ncbi.nlm.nih.gov/pubmed/37084628
http://dx.doi.org/10.1016/j.phymed.2023.154753