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Targeting Aurora-A inhibits tumor progression and sensitizes thyroid carcinoma to Sorafenib by decreasing PFKFB3-mediated glycolysis

Thyroid cancer (TC) is the most common endocrine tumor, amongst which anaplastic thyroid carcinoma (ATC) is the most deadly. Aurora-A usually functions as oncogenes, and its inhibitor Alisertib exerts a powerful antitumor effect in various tumors. However, the mechanism of Aurora-A in regulating TC...

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Detalles Bibliográficos
Autores principales:	Jingtai, Zhi, Linfei, Hu, Yuyang, Qian, Ning, Kang, Xinwei, Yun, Xin, Wang, Xianhui, Ruan, Dongmei, Huang, Weiwei, Yang, Xiangrui, Meng, Tianze, Zhu, Wei, Wang, Xiangqian, Zheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10060208/ https://www.ncbi.nlm.nih.gov/pubmed/36990998 http://dx.doi.org/10.1038/s41419-023-05709-z

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