Interaction analysis of ancestry-enriched variants with APOE-ɛ4 on MCI in the Study of Latinos-Investigation of Neurocognitive Aging

APOE-ɛ4 risk on Mild Cognitive Impairment (MCI) and Alzheimer’s Disease (AD) differs between race/ethnic groups, presumably due to ancestral genomic background surrounding the APOE locus. We studied whether African and Amerindian ancestry-enriched genetic variants in the APOE region modify the effec...

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Detalles Bibliográficos
Autores principales: Granot-Hershkovitz, Einat, Xia, Rui, Yang, Yunju, Spitzer, Brian, Tarraf, Wassim, Vásquez, Priscilla M., Lipton, Richard B., Daviglus, Martha, Argos, Maria, Cai, Jianwen, Kaplan, Robert, Fornage, Myriam, DeCarli, Charles, Gonzalez, Hector M., Sofer, Tamar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10060219/
https://www.ncbi.nlm.nih.gov/pubmed/36991100
http://dx.doi.org/10.1038/s41598-023-32028-2

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