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EQ-5D-5L: a value set for Romania
OBJECTIVE: We aimed to develop an EQ-5D-5L value set for Romania. METHODS: In line with the EuroQoL standardized valuation protocol, computer-assisted interviews were conducted face-to-face in a representative sample in Romania (November 2018–November 2019). Valuation methods included composite time...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Springer Berlin Heidelberg
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10060331/ https://www.ncbi.nlm.nih.gov/pubmed/35688994 http://dx.doi.org/10.1007/s10198-022-01481-7 |
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author | Olariu, Elena Mohammed, Wael Oluboyede, Yemi Caplescu, Raluca Niculescu-Aron, Ileana Gabriela Paveliu, Marian Sorin Vale, Luke |
author_facet | Olariu, Elena Mohammed, Wael Oluboyede, Yemi Caplescu, Raluca Niculescu-Aron, Ileana Gabriela Paveliu, Marian Sorin Vale, Luke |
author_sort | Olariu, Elena |
collection | PubMed |
description | OBJECTIVE: We aimed to develop an EQ-5D-5L value set for Romania. METHODS: In line with the EuroQoL standardized valuation protocol, computer-assisted interviews were conducted face-to-face in a representative sample in Romania (November 2018–November 2019). Valuation methods included composite time trade-off and discrete choice experiment tasks. Several models were tested, including models that accounted for data censoring, panel structure of the data, heteroscedasticity, conditional logit, and hybrid models. The final model was selected based on logical consistency, theoretical considerations, and use of all available data. We compared our value set with other value sets from Central and Eastern Europe region. RESULTS: Data from 1493 respondents was used to estimate the value set. A censored hybrid model corrected for heteroscedasticity was selected to represent the value set. The highest decrements in utility were observed for the pain/discomfort dimension (0.375), followed by the mobility dimension (0.293). Health utilities ranged from 1.000 to − 0.323 and 1.3% of the values were negative. The model was corrected with survey weights to better reflect the representativeness of the sample, but the first two coefficients of the self-care dimension stopped being logically consistent. Differences were found between the Romanian, Hungarian and Polish EQ-5D-5L value sets. Good agreement was noted with the Romanian EQ-5D-3L value set, with a swap between pain/discomfort and mobility in ranking of dimensions. CONCLUSION: A value set for EQ-5D-5L is now available for Romania. This will push one-step further the development of health technology assessment and encourage more health-related quality-of-life research to be conducted locally. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s10198-022-01481-7. |
format | Online Article Text |
id | pubmed-10060331 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-100603312023-03-31 EQ-5D-5L: a value set for Romania Olariu, Elena Mohammed, Wael Oluboyede, Yemi Caplescu, Raluca Niculescu-Aron, Ileana Gabriela Paveliu, Marian Sorin Vale, Luke Eur J Health Econ Original Paper OBJECTIVE: We aimed to develop an EQ-5D-5L value set for Romania. METHODS: In line with the EuroQoL standardized valuation protocol, computer-assisted interviews were conducted face-to-face in a representative sample in Romania (November 2018–November 2019). Valuation methods included composite time trade-off and discrete choice experiment tasks. Several models were tested, including models that accounted for data censoring, panel structure of the data, heteroscedasticity, conditional logit, and hybrid models. The final model was selected based on logical consistency, theoretical considerations, and use of all available data. We compared our value set with other value sets from Central and Eastern Europe region. RESULTS: Data from 1493 respondents was used to estimate the value set. A censored hybrid model corrected for heteroscedasticity was selected to represent the value set. The highest decrements in utility were observed for the pain/discomfort dimension (0.375), followed by the mobility dimension (0.293). Health utilities ranged from 1.000 to − 0.323 and 1.3% of the values were negative. The model was corrected with survey weights to better reflect the representativeness of the sample, but the first two coefficients of the self-care dimension stopped being logically consistent. Differences were found between the Romanian, Hungarian and Polish EQ-5D-5L value sets. Good agreement was noted with the Romanian EQ-5D-3L value set, with a swap between pain/discomfort and mobility in ranking of dimensions. CONCLUSION: A value set for EQ-5D-5L is now available for Romania. This will push one-step further the development of health technology assessment and encourage more health-related quality-of-life research to be conducted locally. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s10198-022-01481-7. Springer Berlin Heidelberg 2022-06-10 2023 /pmc/articles/PMC10060331/ /pubmed/35688994 http://dx.doi.org/10.1007/s10198-022-01481-7 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Original Paper Olariu, Elena Mohammed, Wael Oluboyede, Yemi Caplescu, Raluca Niculescu-Aron, Ileana Gabriela Paveliu, Marian Sorin Vale, Luke EQ-5D-5L: a value set for Romania |
title | EQ-5D-5L: a value set for Romania |
title_full | EQ-5D-5L: a value set for Romania |
title_fullStr | EQ-5D-5L: a value set for Romania |
title_full_unstemmed | EQ-5D-5L: a value set for Romania |
title_short | EQ-5D-5L: a value set for Romania |
title_sort | eq-5d-5l: a value set for romania |
topic | Original Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10060331/ https://www.ncbi.nlm.nih.gov/pubmed/35688994 http://dx.doi.org/10.1007/s10198-022-01481-7 |
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