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Mesenchymal stem cell-derived secretome enhances nucleus pulposus cell metabolism and modulates extracellular matrix gene expression in vitro

Introduction: Intradiscal mesenchymal stromal cell (MSC) therapies for intervertebral disc degeneration (IDD) have been gaining increasing interest due to their capacity to ameliorate intervertebral disc metabolism and relieve low back pain (LBP). Recently, novel investigations have demonstrated tha...

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Detalles Bibliográficos
Autores principales:	Tilotta, Veronica, Vadalà, Gianluca, Ambrosio, Luca, Cicione, Claudia, Di Giacomo, Giuseppina, Russo, Fabrizio, Papalia, Rocco, Denaro, Vincenzo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Bioengineering and Biotechnology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10060656/ https://www.ncbi.nlm.nih.gov/pubmed/37008028 http://dx.doi.org/10.3389/fbioe.2023.1152207

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