The effect of allyl isothiocyanate on chondrocyte phenotype is matrix stiffness-dependent: Possible involvement of TRPA1 activation

Osteoarthritis (OA) is a chronic joint disease with increasing prevalence. Chondrocytes (CHs) are highly differentiated end-stage cells with a secretory phenotype that keeps the extracellular matrix (ECM) balanced and the cartilage environment stable. Osteoarthritis dedifferentiation causes cartilag...

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Detalles Bibliográficos
Autores principales: Che, Hui, Shao, Zhiqiang, Ding, Jiangchen, Gao, Hua, Liu, Xiangyu, Chen, Hailong, Cai, Shuangyu, Ge, Jiaying, Wang, Chengqiang, Wu, Jun, Hao, Yuefeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10060966/
https://www.ncbi.nlm.nih.gov/pubmed/37006615
http://dx.doi.org/10.3389/fmolb.2023.1112653

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