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Maternal genetic polymorphisms in the major mitotic checkpoint genes MAD1L1 and MAD2L1 associated with the risk of survival in abnormal chromosomal fetuses
Background: The genetic etiology of fetal chromosome abnormalities remains unknown, which brings about an enormous burden for patients, families, and society. The spindle assembly checkpoint (SAC) controls the normal procedure of chromosome disjunction and may take part in the process. Objective: Th...
Autores principales: | Chan, Ying, Liu, Yize, Kong, Yamin, Xu, Weiming, Zeng, Xiaohong, Li, Haichun, Guo, Yan, Tang, Xinhua, Zhang, Jinman, Zhu, Baosheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10061030/ https://www.ncbi.nlm.nih.gov/pubmed/37007941 http://dx.doi.org/10.3389/fgene.2023.1105184 |
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