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Exploiting embryonic niche conditions to grow Wilms tumor blastema in culture

INTRODUCTION: Wilms Tumor (WT), or nephroblastoma, is the most common pediatric kidney cancer. Most WTs display a “favorable” triphasic histology, in which the tumor is comprised of blastemal, stromal, and epithelial cell types. Blastemal predominance after neoadjuvant chemotherapy or diffuse anapla...

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Detalles Bibliográficos
Autores principales: Wojcik, Heather M., Lovvorn, Harold N., Hollingshead, Melinda, Pierce, Janene, Stotler, Howard, Murphy, Andrew J., Borgel, Suzanne, Phelps, Hannah M., Correa, Hernan, Perantoni, Alan O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10061139/
https://www.ncbi.nlm.nih.gov/pubmed/37007076
http://dx.doi.org/10.3389/fonc.2023.1091274

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