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Bicarbonate transport as regulator of antitumour immunity in pancreatic cancer

Bicarbonate transport is a pre‐existing mechanism of pH regulation in pancreatic ductal cells. In a recent study, Cappellesso et al. demonstrated that pancreatic ductal adenocarcinoma metabolic rewiring creates an acidic environment, enhanced by bicarbonate import into cancer cells via SLC4A4. This...

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Detalles Bibliográficos
Autores principales: Kay, Emily J., Zanivan, Sara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10061281/
https://www.ncbi.nlm.nih.gov/pubmed/36807529
http://dx.doi.org/10.1002/1878-0261.13400