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Rediscovery of Tetronomycin as a Broad-Spectrum and Potent Antibiotic against Drug-Resistant Gram-Positive Bacteria

[Image: see text] Tetronomycin (1), first isolated from a cultured broth of Streptomyces sp. by Juslen et al. in 1974, is a polycyclic polyether compound. However, the biological activity of 1 has not been thoroughly examined. In this study, we found that 1 exhibits more potent antibacterial activit...

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Detalles Bibliográficos
Autores principales: Kimishima, Aoi, Tsuruoka, Iori, Kanto, Hiroki, Tsutsumi, Hayama, Arima, Naoaki, Sakai, Kazunari, Sugamata, Miho, Matsui, Hidehito, Watanabe, Yoshihiro, Iwatsuki, Masato, Honsho, Masako, Naher, Kamrun, Inahashi, Yuki, Hanaki, Hideaki, Asami, Yukihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10061530/
https://www.ncbi.nlm.nih.gov/pubmed/37008151
http://dx.doi.org/10.1021/acsomega.3c00651