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E-Cigarette Liquids and Aldehyde Flavoring Agents Inhibit CYP2A6 Activity in Lung Epithelial Cells
[Image: see text] Certain e-liquids and aromatic aldehyde flavoring agents were previously identified as inhibitors of microsomal recombinant CYP2A6, the primary nicotine-metabolizing enzyme. However, due to their reactive nature, aldehydes may react with cellular components before reaching CYP2A6 i...
Autores principales: | Winters, Brett R., Clapp, Phillip W., Simmons, Steven O., Kochar, Tavleen K., Jaspers, Ilona, Madden, Michael C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10061538/ https://www.ncbi.nlm.nih.gov/pubmed/37008141 http://dx.doi.org/10.1021/acsomega.2c08258 |
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