Hyponatremia as a Predictor of Cryptococcal Meningitis and Death Among Asymptomatic Persons With HIV and Cryptococcal Antigenemia

Among persons with human immunodeficiency virus–associated cryptococcal meningitis serum hyponatremia is a risk factor for mortality; however, the role of hyponatremia in persons with asymptomatic cryptococcal antigenemia is unknown. We found that serum hyponatremia ≤130 mmol/L is an independent ris...

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Autores principales: Lehman, Alice, Nalintya, Elizabeth, Wele, Abduljewad, Kirumira, Paul, Naluyima, Rose, Namuli, Teopista, Turya Musa, Fred, Skipper, Caleb P, Meya, David B, Boulware, David R, Rajasingham, Radha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10061560/
https://www.ncbi.nlm.nih.gov/pubmed/37008569
http://dx.doi.org/10.1093/ofid/ofad156
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author Lehman, Alice
Nalintya, Elizabeth
Wele, Abduljewad
Kirumira, Paul
Naluyima, Rose
Namuli, Teopista
Turya Musa, Fred
Skipper, Caleb P
Meya, David B
Boulware, David R
Rajasingham, Radha
author_facet Lehman, Alice
Nalintya, Elizabeth
Wele, Abduljewad
Kirumira, Paul
Naluyima, Rose
Namuli, Teopista
Turya Musa, Fred
Skipper, Caleb P
Meya, David B
Boulware, David R
Rajasingham, Radha
author_sort Lehman, Alice
collection PubMed
description Among persons with human immunodeficiency virus–associated cryptococcal meningitis serum hyponatremia is a risk factor for mortality; however, the role of hyponatremia in persons with asymptomatic cryptococcal antigenemia is unknown. We found that serum hyponatremia ≤130 mmol/L is an independent risk factor for progression to meningitis and death in asymptomatic persons with cryptococcal antigenemia with low titers.
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spelling pubmed-100615602023-03-31 Hyponatremia as a Predictor of Cryptococcal Meningitis and Death Among Asymptomatic Persons With HIV and Cryptococcal Antigenemia Lehman, Alice Nalintya, Elizabeth Wele, Abduljewad Kirumira, Paul Naluyima, Rose Namuli, Teopista Turya Musa, Fred Skipper, Caleb P Meya, David B Boulware, David R Rajasingham, Radha Open Forum Infect Dis Brief Report Among persons with human immunodeficiency virus–associated cryptococcal meningitis serum hyponatremia is a risk factor for mortality; however, the role of hyponatremia in persons with asymptomatic cryptococcal antigenemia is unknown. We found that serum hyponatremia ≤130 mmol/L is an independent risk factor for progression to meningitis and death in asymptomatic persons with cryptococcal antigenemia with low titers. Oxford University Press 2023-03-28 /pmc/articles/PMC10061560/ /pubmed/37008569 http://dx.doi.org/10.1093/ofid/ofad156 Text en © The Author(s) 2023. Published by Oxford University Press on behalf of Infectious Diseases Society of America. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (https://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Brief Report
Lehman, Alice
Nalintya, Elizabeth
Wele, Abduljewad
Kirumira, Paul
Naluyima, Rose
Namuli, Teopista
Turya Musa, Fred
Skipper, Caleb P
Meya, David B
Boulware, David R
Rajasingham, Radha
Hyponatremia as a Predictor of Cryptococcal Meningitis and Death Among Asymptomatic Persons With HIV and Cryptococcal Antigenemia
title Hyponatremia as a Predictor of Cryptococcal Meningitis and Death Among Asymptomatic Persons With HIV and Cryptococcal Antigenemia
title_full Hyponatremia as a Predictor of Cryptococcal Meningitis and Death Among Asymptomatic Persons With HIV and Cryptococcal Antigenemia
title_fullStr Hyponatremia as a Predictor of Cryptococcal Meningitis and Death Among Asymptomatic Persons With HIV and Cryptococcal Antigenemia
title_full_unstemmed Hyponatremia as a Predictor of Cryptococcal Meningitis and Death Among Asymptomatic Persons With HIV and Cryptococcal Antigenemia
title_short Hyponatremia as a Predictor of Cryptococcal Meningitis and Death Among Asymptomatic Persons With HIV and Cryptococcal Antigenemia
title_sort hyponatremia as a predictor of cryptococcal meningitis and death among asymptomatic persons with hiv and cryptococcal antigenemia
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10061560/
https://www.ncbi.nlm.nih.gov/pubmed/37008569
http://dx.doi.org/10.1093/ofid/ofad156
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