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Magnetically Powered Chitosan Milliwheels for Rapid Translation, Barrier Function Rescue, and Delivery of Therapeutic Proteins to the Inflamed Gut Epithelium

[Image: see text] Inflammatory bowel disease (IBD) is mediated by an overexpression of tumor necrosis factor-α (TNF) by mononuclear cells in the intestinal mucosa. Intravenous delivery of neutralizing anti-TNF antibodies can cause systemic immunosuppression, and up to one-third of people are non-res...

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Detalles Bibliográficos
Autores principales: Osmond, Matthew J., Korthals, Elizabeth, Zimmermann, Coy J., Roth, Eric J., Marr, David W.M., Neeves, Keith B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10061643/
https://www.ncbi.nlm.nih.gov/pubmed/37008083
http://dx.doi.org/10.1021/acsomega.3c00886