Visible-Light-Promoted Direct C3-H Cyanomethylation of 2H-Indazoles

[Image: see text] The efficient visible-light-promoted cyanomethylation of 2H-indazoles in the presence of Ir(ppy)(3) as the photocatalyst and bromoacetonitrile as the cyanomethyl radical source was achieved under mild conditions, providing a series of C3-cyanomethylated derivatives in good yields.

Detalles Bibliográficos
Autores principales: Mi, Xia, Cui, Beibei, Song, Jinqing, Zhang, Jingyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10061648/
https://www.ncbi.nlm.nih.gov/pubmed/37008106
http://dx.doi.org/10.1021/acsomega.2c08094
Descripción
Sumario:[Image: see text] The efficient visible-light-promoted cyanomethylation of 2H-indazoles in the presence of Ir(ppy)(3) as the photocatalyst and bromoacetonitrile as the cyanomethyl radical source was achieved under mild conditions, providing a series of C3-cyanomethylated derivatives in good yields.

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