Visible-Light-Promoted Direct C3-H Cyanomethylation of 2H-Indazoles

[Image: see text] The efficient visible-light-promoted cyanomethylation of 2H-indazoles in the presence of Ir(ppy)(3) as the photocatalyst and bromoacetonitrile as the cyanomethyl radical source was achieved under mild conditions, providing a series of C3-cyanomethylated derivatives in good yields.

Detalles Bibliográficos
Autores principales: Mi, Xia, Cui, Beibei, Song, Jinqing, Zhang, Jingyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10061648/
https://www.ncbi.nlm.nih.gov/pubmed/37008106
http://dx.doi.org/10.1021/acsomega.2c08094
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author Mi, Xia
Cui, Beibei
Song, Jinqing
Zhang, Jingyu
author_facet Mi, Xia
Cui, Beibei
Song, Jinqing
Zhang, Jingyu
author_sort Mi, Xia
collection PubMed
description [Image: see text] The efficient visible-light-promoted cyanomethylation of 2H-indazoles in the presence of Ir(ppy)(3) as the photocatalyst and bromoacetonitrile as the cyanomethyl radical source was achieved under mild conditions, providing a series of C3-cyanomethylated derivatives in good yields.
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spelling pubmed-100616482023-03-31 Visible-Light-Promoted Direct C3-H Cyanomethylation of 2H-Indazoles Mi, Xia Cui, Beibei Song, Jinqing Zhang, Jingyu ACS Omega [Image: see text] The efficient visible-light-promoted cyanomethylation of 2H-indazoles in the presence of Ir(ppy)(3) as the photocatalyst and bromoacetonitrile as the cyanomethyl radical source was achieved under mild conditions, providing a series of C3-cyanomethylated derivatives in good yields. American Chemical Society 2023-03-13 /pmc/articles/PMC10061648/ /pubmed/37008106 http://dx.doi.org/10.1021/acsomega.2c08094 Text en © 2023 The Authors. Published by American Chemical Society https://creativecommons.org/licenses/by-nc-nd/4.0/Permits non-commercial access and re-use, provided that author attribution and integrity are maintained; but does not permit creation of adaptations or other derivative works (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Mi, Xia
Cui, Beibei
Song, Jinqing
Zhang, Jingyu
Visible-Light-Promoted Direct C3-H Cyanomethylation of 2H-Indazoles
title Visible-Light-Promoted Direct C3-H Cyanomethylation of 2H-Indazoles
title_full Visible-Light-Promoted Direct C3-H Cyanomethylation of 2H-Indazoles
title_fullStr Visible-Light-Promoted Direct C3-H Cyanomethylation of 2H-Indazoles
title_full_unstemmed Visible-Light-Promoted Direct C3-H Cyanomethylation of 2H-Indazoles
title_short Visible-Light-Promoted Direct C3-H Cyanomethylation of 2H-Indazoles
title_sort visible-light-promoted direct c3-h cyanomethylation of 2h-indazoles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10061648/
https://www.ncbi.nlm.nih.gov/pubmed/37008106
http://dx.doi.org/10.1021/acsomega.2c08094
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AT zhangjingyu visiblelightpromoteddirectc3hcyanomethylationof2hindazoles

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