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LATE ONSET CANDIDA KRUSEI SEPTICAEMIA IN A NEONATE WHICH RESPONDED TO FLUCONAZOLE MONOTHERAPY: A CASE REPORT

Systemic candida infections in the neonatal population are commonly seen especially in low birth weight, preterm neonates admitted to the Neonatal Intensive Care Unit. Albicans spp is the most commonly isolated but in more recent times, fluconazole resistant spp such as Candida krusei have been repo...

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Autores principales: Adigun, M.B., Akindolire, A.E., Adedeji, W.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Association of Resident Doctors (ARD), University College Hospital, Ibadan 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10061664/
https://www.ncbi.nlm.nih.gov/pubmed/37006648
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author Adigun, M.B.
Akindolire, A.E.
Adedeji, W.A.
author_facet Adigun, M.B.
Akindolire, A.E.
Adedeji, W.A.
author_sort Adigun, M.B.
collection PubMed
description Systemic candida infections in the neonatal population are commonly seen especially in low birth weight, preterm neonates admitted to the Neonatal Intensive Care Unit. Albicans spp is the most commonly isolated but in more recent times, fluconazole resistant spp such as Candida krusei have been reported to cause healthcare associated infections. This is a case of a 12-day old, term, low birth weight (2.45 kg), male neonate delivered to a 32-year-old [Formula: see text] through elective caesarian section (CS) at term. He was well till the 12th day of life when he developed respiratory distress and sub-optimal oxygen saturation requiring supplemental oxygen. Chest x-ray showed prominent vascular markings with no active focal lung lesion and he was managed for suspected Aspiration Pneumonitis until a blood culture on the 10th day of admission yielded Candida krusei . He had a monotherapy of intravenous fluconazole, made progressive clinical improvement and was discharged on oral fluconazole to complete a 6 weeks course on outpatient basis.
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spelling pubmed-100616642023-03-31 LATE ONSET CANDIDA KRUSEI SEPTICAEMIA IN A NEONATE WHICH RESPONDED TO FLUCONAZOLE MONOTHERAPY: A CASE REPORT Adigun, M.B. Akindolire, A.E. Adedeji, W.A. Ann Ib Postgrad Med Original Article Systemic candida infections in the neonatal population are commonly seen especially in low birth weight, preterm neonates admitted to the Neonatal Intensive Care Unit. Albicans spp is the most commonly isolated but in more recent times, fluconazole resistant spp such as Candida krusei have been reported to cause healthcare associated infections. This is a case of a 12-day old, term, low birth weight (2.45 kg), male neonate delivered to a 32-year-old [Formula: see text] through elective caesarian section (CS) at term. He was well till the 12th day of life when he developed respiratory distress and sub-optimal oxygen saturation requiring supplemental oxygen. Chest x-ray showed prominent vascular markings with no active focal lung lesion and he was managed for suspected Aspiration Pneumonitis until a blood culture on the 10th day of admission yielded Candida krusei . He had a monotherapy of intravenous fluconazole, made progressive clinical improvement and was discharged on oral fluconazole to complete a 6 weeks course on outpatient basis. Association of Resident Doctors (ARD), University College Hospital, Ibadan 2022-06 /pmc/articles/PMC10061664/ /pubmed/37006648 Text en © Association of Resident Doctors, UCH, Ibadan https://creativecommons.org/licenses/by-nc/3.0/This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
spellingShingle Original Article
Adigun, M.B.
Akindolire, A.E.
Adedeji, W.A.
LATE ONSET CANDIDA KRUSEI SEPTICAEMIA IN A NEONATE WHICH RESPONDED TO FLUCONAZOLE MONOTHERAPY: A CASE REPORT
title LATE ONSET CANDIDA KRUSEI SEPTICAEMIA IN A NEONATE WHICH RESPONDED TO FLUCONAZOLE MONOTHERAPY: A CASE REPORT
title_full LATE ONSET CANDIDA KRUSEI SEPTICAEMIA IN A NEONATE WHICH RESPONDED TO FLUCONAZOLE MONOTHERAPY: A CASE REPORT
title_fullStr LATE ONSET CANDIDA KRUSEI SEPTICAEMIA IN A NEONATE WHICH RESPONDED TO FLUCONAZOLE MONOTHERAPY: A CASE REPORT
title_full_unstemmed LATE ONSET CANDIDA KRUSEI SEPTICAEMIA IN A NEONATE WHICH RESPONDED TO FLUCONAZOLE MONOTHERAPY: A CASE REPORT
title_short LATE ONSET CANDIDA KRUSEI SEPTICAEMIA IN A NEONATE WHICH RESPONDED TO FLUCONAZOLE MONOTHERAPY: A CASE REPORT
title_sort late onset candida krusei septicaemia in a neonate which responded to fluconazole monotherapy: a case report
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10061664/
https://www.ncbi.nlm.nih.gov/pubmed/37006648
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