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LATE ONSET CANDIDA KRUSEI SEPTICAEMIA IN A NEONATE WHICH RESPONDED TO FLUCONAZOLE MONOTHERAPY: A CASE REPORT
Systemic candida infections in the neonatal population are commonly seen especially in low birth weight, preterm neonates admitted to the Neonatal Intensive Care Unit. Albicans spp is the most commonly isolated but in more recent times, fluconazole resistant spp such as Candida krusei have been repo...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Association of Resident Doctors (ARD), University College Hospital, Ibadan
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10061664/ https://www.ncbi.nlm.nih.gov/pubmed/37006648 |
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author | Adigun, M.B. Akindolire, A.E. Adedeji, W.A. |
author_facet | Adigun, M.B. Akindolire, A.E. Adedeji, W.A. |
author_sort | Adigun, M.B. |
collection | PubMed |
description | Systemic candida infections in the neonatal population are commonly seen especially in low birth weight, preterm neonates admitted to the Neonatal Intensive Care Unit. Albicans spp is the most commonly isolated but in more recent times, fluconazole resistant spp such as Candida krusei have been reported to cause healthcare associated infections. This is a case of a 12-day old, term, low birth weight (2.45 kg), male neonate delivered to a 32-year-old [Formula: see text] through elective caesarian section (CS) at term. He was well till the 12th day of life when he developed respiratory distress and sub-optimal oxygen saturation requiring supplemental oxygen. Chest x-ray showed prominent vascular markings with no active focal lung lesion and he was managed for suspected Aspiration Pneumonitis until a blood culture on the 10th day of admission yielded Candida krusei . He had a monotherapy of intravenous fluconazole, made progressive clinical improvement and was discharged on oral fluconazole to complete a 6 weeks course on outpatient basis. |
format | Online Article Text |
id | pubmed-10061664 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Association of Resident Doctors (ARD), University College Hospital, Ibadan |
record_format | MEDLINE/PubMed |
spelling | pubmed-100616642023-03-31 LATE ONSET CANDIDA KRUSEI SEPTICAEMIA IN A NEONATE WHICH RESPONDED TO FLUCONAZOLE MONOTHERAPY: A CASE REPORT Adigun, M.B. Akindolire, A.E. Adedeji, W.A. Ann Ib Postgrad Med Original Article Systemic candida infections in the neonatal population are commonly seen especially in low birth weight, preterm neonates admitted to the Neonatal Intensive Care Unit. Albicans spp is the most commonly isolated but in more recent times, fluconazole resistant spp such as Candida krusei have been reported to cause healthcare associated infections. This is a case of a 12-day old, term, low birth weight (2.45 kg), male neonate delivered to a 32-year-old [Formula: see text] through elective caesarian section (CS) at term. He was well till the 12th day of life when he developed respiratory distress and sub-optimal oxygen saturation requiring supplemental oxygen. Chest x-ray showed prominent vascular markings with no active focal lung lesion and he was managed for suspected Aspiration Pneumonitis until a blood culture on the 10th day of admission yielded Candida krusei . He had a monotherapy of intravenous fluconazole, made progressive clinical improvement and was discharged on oral fluconazole to complete a 6 weeks course on outpatient basis. Association of Resident Doctors (ARD), University College Hospital, Ibadan 2022-06 /pmc/articles/PMC10061664/ /pubmed/37006648 Text en © Association of Resident Doctors, UCH, Ibadan https://creativecommons.org/licenses/by-nc/3.0/This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited. |
spellingShingle | Original Article Adigun, M.B. Akindolire, A.E. Adedeji, W.A. LATE ONSET CANDIDA KRUSEI SEPTICAEMIA IN A NEONATE WHICH RESPONDED TO FLUCONAZOLE MONOTHERAPY: A CASE REPORT |
title | LATE ONSET CANDIDA KRUSEI SEPTICAEMIA IN A NEONATE WHICH RESPONDED TO FLUCONAZOLE MONOTHERAPY: A CASE REPORT |
title_full | LATE ONSET CANDIDA KRUSEI SEPTICAEMIA IN A NEONATE WHICH RESPONDED TO FLUCONAZOLE MONOTHERAPY: A CASE REPORT |
title_fullStr | LATE ONSET CANDIDA KRUSEI SEPTICAEMIA IN A NEONATE WHICH RESPONDED TO FLUCONAZOLE MONOTHERAPY: A CASE REPORT |
title_full_unstemmed | LATE ONSET CANDIDA KRUSEI SEPTICAEMIA IN A NEONATE WHICH RESPONDED TO FLUCONAZOLE MONOTHERAPY: A CASE REPORT |
title_short | LATE ONSET CANDIDA KRUSEI SEPTICAEMIA IN A NEONATE WHICH RESPONDED TO FLUCONAZOLE MONOTHERAPY: A CASE REPORT |
title_sort | late onset candida krusei septicaemia in a neonate which responded to fluconazole monotherapy: a case report |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10061664/ https://www.ncbi.nlm.nih.gov/pubmed/37006648 |
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