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The shaky foundations of simulating single-cell RNA sequencing data
BACKGROUND: With the emergence of hundreds of single-cell RNA-sequencing (scRNA-seq) datasets, the number of computational tools to analyze aspects of the generated data has grown rapidly. As a result, there is a recurring need to demonstrate whether newly developed methods are truly performant—on t...
Autores principales: | Crowell, Helena L., Morillo Leonardo, Sarah X., Soneson, Charlotte, Robinson, Mark D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10061781/ https://www.ncbi.nlm.nih.gov/pubmed/36991470 http://dx.doi.org/10.1186/s13059-023-02904-1 |
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