CD248 promotes migration and metastasis of osteosarcoma through ITGB1-mediated FAK-paxillin pathway activation

BACKGROUND: Osteosarcoma (OS) is the most common malignant bone tumor with a high incidence in children and adolescents. Frequent tumor metastasis and high postoperative recurrence are the most common challenges in OS. However, detailed mechanism is largely unknown. METHODS: We examined the expressi...

Descripción completa

Detalles Bibliográficos
Autores principales: Lu, Shiqi, Lu, Tong, Zhang, Jiayu, Gan, Lunbiao, Wu, Xinjie, Han, Donghui, Zhang, Keying, Xu, Chao, Liu, Shaojie, Qin, Weijun, Yang, Fa, Wen, Weihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10061858/
https://www.ncbi.nlm.nih.gov/pubmed/36997926
http://dx.doi.org/10.1186/s12885-023-10731-7

Ejemplares similares

Ejemplares similares