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Hospital mortality of blunt abdominal aortic injury (BAAI): a systematic review and meta-analysis
BACKGROUND: Studies on the mortality of blunt abdominal aortic injury (BAAI) are rare and have yielded inconsistent results. In the present study, we aimed to quantitatively analyse the retrieved data to more accurately determine the hospital mortality of BAAI. METHODS: The Excerpta Medica Database,...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10061949/ https://www.ncbi.nlm.nih.gov/pubmed/36991444 http://dx.doi.org/10.1186/s13017-023-00492-w |
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author | Li, Mingxuan Yan, Yu Wang, Chaonan Tu, Haixia |
author_facet | Li, Mingxuan Yan, Yu Wang, Chaonan Tu, Haixia |
author_sort | Li, Mingxuan |
collection | PubMed |
description | BACKGROUND: Studies on the mortality of blunt abdominal aortic injury (BAAI) are rare and have yielded inconsistent results. In the present study, we aimed to quantitatively analyse the retrieved data to more accurately determine the hospital mortality of BAAI. METHODS: The Excerpta Medica Database, PubMed, Web of Science and Cochrane Library databases were searched to identify relevant publications without date restrictions. The overall hospital mortality (OHM) of BAAI patients was set as the primary outcome measure. English publications with data that met the selection criteria were included. The quality of all included studies was assessed by the Joanna Briggs Institute checklist and the American Agency for Health Care Quality and Research’s cross-sectional study quality evaluation items. After data extraction, a meta-analysis of the Freeman–Tukey double arcsine transformation of data was performed using the Metaprop command in Stata 16 software. Heterogeneity was assessed and reported as a percentage using the I(2) index value and as a P value using the Cochrane Q test. Various methods were used to determine the sources of heterogeneity and to analyse the sensitivity of the computation model. RESULTS: Of the 2147 references screened, 5 studies that involved 1593 patients met the selection criteria and were included. There were no low-quality references after assessment. One study that only included 16 juvenile BAAI patients was excluded from the meta-analysis of the primary outcome measure due to high heterogeneity. Due to the low heterogeneity (I(2) = 47.6%, P = 0.126 for Q test) that was observed after using the random effects model, the fixed model was subsequently used to pool the effect sizes of the remaining four studies, thus yielding an OHM of 28.8% [95% confidence interval (CI) 26.5–31.1%]. The stability of the model was verified by sensitivity analysis, and Egger’s test (P = 0.339) indicated a low level of publication bias. In addition, we also performed meta-analyses and obtained a pooled hospital mortality of operation (13.5%, 95% CI 8.0–20.0%), a pooled hospital mortality of non-operation (28.4%, 95% CI 25.9–31.0%), and a pooled rate of aortic rupture (12.2%, 95% CI 7.0–18.5%) of BAAI. CONCLUSIONS: The present study indicated that BAAI has an OHM of 28.8%, indicating that this disease deserves more attention and research. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s13017-023-00492-w. |
format | Online Article Text |
id | pubmed-10061949 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-100619492023-03-31 Hospital mortality of blunt abdominal aortic injury (BAAI): a systematic review and meta-analysis Li, Mingxuan Yan, Yu Wang, Chaonan Tu, Haixia World J Emerg Surg Research BACKGROUND: Studies on the mortality of blunt abdominal aortic injury (BAAI) are rare and have yielded inconsistent results. In the present study, we aimed to quantitatively analyse the retrieved data to more accurately determine the hospital mortality of BAAI. METHODS: The Excerpta Medica Database, PubMed, Web of Science and Cochrane Library databases were searched to identify relevant publications without date restrictions. The overall hospital mortality (OHM) of BAAI patients was set as the primary outcome measure. English publications with data that met the selection criteria were included. The quality of all included studies was assessed by the Joanna Briggs Institute checklist and the American Agency for Health Care Quality and Research’s cross-sectional study quality evaluation items. After data extraction, a meta-analysis of the Freeman–Tukey double arcsine transformation of data was performed using the Metaprop command in Stata 16 software. Heterogeneity was assessed and reported as a percentage using the I(2) index value and as a P value using the Cochrane Q test. Various methods were used to determine the sources of heterogeneity and to analyse the sensitivity of the computation model. RESULTS: Of the 2147 references screened, 5 studies that involved 1593 patients met the selection criteria and were included. There were no low-quality references after assessment. One study that only included 16 juvenile BAAI patients was excluded from the meta-analysis of the primary outcome measure due to high heterogeneity. Due to the low heterogeneity (I(2) = 47.6%, P = 0.126 for Q test) that was observed after using the random effects model, the fixed model was subsequently used to pool the effect sizes of the remaining four studies, thus yielding an OHM of 28.8% [95% confidence interval (CI) 26.5–31.1%]. The stability of the model was verified by sensitivity analysis, and Egger’s test (P = 0.339) indicated a low level of publication bias. In addition, we also performed meta-analyses and obtained a pooled hospital mortality of operation (13.5%, 95% CI 8.0–20.0%), a pooled hospital mortality of non-operation (28.4%, 95% CI 25.9–31.0%), and a pooled rate of aortic rupture (12.2%, 95% CI 7.0–18.5%) of BAAI. CONCLUSIONS: The present study indicated that BAAI has an OHM of 28.8%, indicating that this disease deserves more attention and research. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s13017-023-00492-w. BioMed Central 2023-03-29 /pmc/articles/PMC10061949/ /pubmed/36991444 http://dx.doi.org/10.1186/s13017-023-00492-w Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Li, Mingxuan Yan, Yu Wang, Chaonan Tu, Haixia Hospital mortality of blunt abdominal aortic injury (BAAI): a systematic review and meta-analysis |
title | Hospital mortality of blunt abdominal aortic injury (BAAI): a systematic review and meta-analysis |
title_full | Hospital mortality of blunt abdominal aortic injury (BAAI): a systematic review and meta-analysis |
title_fullStr | Hospital mortality of blunt abdominal aortic injury (BAAI): a systematic review and meta-analysis |
title_full_unstemmed | Hospital mortality of blunt abdominal aortic injury (BAAI): a systematic review and meta-analysis |
title_short | Hospital mortality of blunt abdominal aortic injury (BAAI): a systematic review and meta-analysis |
title_sort | hospital mortality of blunt abdominal aortic injury (baai): a systematic review and meta-analysis |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10061949/ https://www.ncbi.nlm.nih.gov/pubmed/36991444 http://dx.doi.org/10.1186/s13017-023-00492-w |
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