Cargando…
Vertebral bone quality score to predict cage subsidence following oblique lumbar interbody fusion
BACKGROUND: Current evidence suggests that the magnetic resonance imaging (MRI)-based vertebral bone quality (VBQ) score is a good parameter for evaluating bone quality. We aimed to assess whether the VBQ score can predict the occurrence of postoperative cage subsidence after oblique lumbar interbod...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10061981/ https://www.ncbi.nlm.nih.gov/pubmed/36991489 http://dx.doi.org/10.1186/s13018-023-03729-1 |
_version_ | 1785017402839269376 |
---|---|
author | Huang, Yong Chen, Qian Liu, Limin Feng, Ganjun |
author_facet | Huang, Yong Chen, Qian Liu, Limin Feng, Ganjun |
author_sort | Huang, Yong |
collection | PubMed |
description | BACKGROUND: Current evidence suggests that the magnetic resonance imaging (MRI)-based vertebral bone quality (VBQ) score is a good parameter for evaluating bone quality. We aimed to assess whether the VBQ score can predict the occurrence of postoperative cage subsidence after oblique lumbar interbody fusion (OLIF) surgery. METHODS: Patients (n = 102) who had undergone single-level OLIF with a minimal follow-up for 1 year were reviewed in this study. Demographic and radiographic data of these patients were collected. Cage subsidence was defined as ≥ 2 mm of cage migration into the inferior endplate, superior endplate, or both. Further, the MRI-based VBQ score was measured on T1-weighted images. Moreover, univariable and multivariable binary logistic regression analyses were performed. Meanwhile, Pearson analysis was used to evaluate the correlation among the VBQ score, average lumbar dual-energy X-ray absorptiometry (DEXA) T-score, and degree of cage subsidence. Furthermore, ad-hoc analysis was used along with receiver operating characteristic curve analysis to assess the predictive ability of the VBQ score and average lumbar DEXA T-score. RESULTS: Of 102 participants, cage subsidence was observed in 39 (38.24%) patients. According to the univariable analysis, patients with subsidence had older age, higher antiosteoporotic drug use, larger disk height change, a more concave morphology of inferior and superior endplates, higher VBQ score, and lower average lumbar DEXA T-score compared to patients without subsidence. In the multivariable logistic regression analysis, a higher VBQ score was significantly associated with an increased risk of subsidence (OR = 23.158 ± 0.849, 95% CI 4.381–122.399, p < 0.001), and it was the only significant and independent predictor of subsidence after OLIF. Moreover, the VBQ score was moderately correlated with the average lumbar DEXA T-score (r = − 0.576, p < 0.001) and the amount of cage subsidence (r = 0.649, p < 0.001). Furthermore, this score significantly predicted cage subsidence with an accuracy of 83.9%. CONCLUSIONS: The VBQ score can independently predict postoperative cage subsidence in patients undergoing OLIF surgery. |
format | Online Article Text |
id | pubmed-10061981 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-100619812023-03-31 Vertebral bone quality score to predict cage subsidence following oblique lumbar interbody fusion Huang, Yong Chen, Qian Liu, Limin Feng, Ganjun J Orthop Surg Res Research Article BACKGROUND: Current evidence suggests that the magnetic resonance imaging (MRI)-based vertebral bone quality (VBQ) score is a good parameter for evaluating bone quality. We aimed to assess whether the VBQ score can predict the occurrence of postoperative cage subsidence after oblique lumbar interbody fusion (OLIF) surgery. METHODS: Patients (n = 102) who had undergone single-level OLIF with a minimal follow-up for 1 year were reviewed in this study. Demographic and radiographic data of these patients were collected. Cage subsidence was defined as ≥ 2 mm of cage migration into the inferior endplate, superior endplate, or both. Further, the MRI-based VBQ score was measured on T1-weighted images. Moreover, univariable and multivariable binary logistic regression analyses were performed. Meanwhile, Pearson analysis was used to evaluate the correlation among the VBQ score, average lumbar dual-energy X-ray absorptiometry (DEXA) T-score, and degree of cage subsidence. Furthermore, ad-hoc analysis was used along with receiver operating characteristic curve analysis to assess the predictive ability of the VBQ score and average lumbar DEXA T-score. RESULTS: Of 102 participants, cage subsidence was observed in 39 (38.24%) patients. According to the univariable analysis, patients with subsidence had older age, higher antiosteoporotic drug use, larger disk height change, a more concave morphology of inferior and superior endplates, higher VBQ score, and lower average lumbar DEXA T-score compared to patients without subsidence. In the multivariable logistic regression analysis, a higher VBQ score was significantly associated with an increased risk of subsidence (OR = 23.158 ± 0.849, 95% CI 4.381–122.399, p < 0.001), and it was the only significant and independent predictor of subsidence after OLIF. Moreover, the VBQ score was moderately correlated with the average lumbar DEXA T-score (r = − 0.576, p < 0.001) and the amount of cage subsidence (r = 0.649, p < 0.001). Furthermore, this score significantly predicted cage subsidence with an accuracy of 83.9%. CONCLUSIONS: The VBQ score can independently predict postoperative cage subsidence in patients undergoing OLIF surgery. BioMed Central 2023-03-30 /pmc/articles/PMC10061981/ /pubmed/36991489 http://dx.doi.org/10.1186/s13018-023-03729-1 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Research Article Huang, Yong Chen, Qian Liu, Limin Feng, Ganjun Vertebral bone quality score to predict cage subsidence following oblique lumbar interbody fusion |
title | Vertebral bone quality score to predict cage subsidence following oblique lumbar interbody fusion |
title_full | Vertebral bone quality score to predict cage subsidence following oblique lumbar interbody fusion |
title_fullStr | Vertebral bone quality score to predict cage subsidence following oblique lumbar interbody fusion |
title_full_unstemmed | Vertebral bone quality score to predict cage subsidence following oblique lumbar interbody fusion |
title_short | Vertebral bone quality score to predict cage subsidence following oblique lumbar interbody fusion |
title_sort | vertebral bone quality score to predict cage subsidence following oblique lumbar interbody fusion |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10061981/ https://www.ncbi.nlm.nih.gov/pubmed/36991489 http://dx.doi.org/10.1186/s13018-023-03729-1 |
work_keys_str_mv | AT huangyong vertebralbonequalityscoretopredictcagesubsidencefollowingobliquelumbarinterbodyfusion AT chenqian vertebralbonequalityscoretopredictcagesubsidencefollowingobliquelumbarinterbodyfusion AT liulimin vertebralbonequalityscoretopredictcagesubsidencefollowingobliquelumbarinterbodyfusion AT fengganjun vertebralbonequalityscoretopredictcagesubsidencefollowingobliquelumbarinterbodyfusion |