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Analysis of the Effect of Polymorphisms within the CATHL7 Gene on Dairy Performance Parameters

INTRODUCTION: Antimicrobial peptides, including cathelicidins, play a significant role in farm animals, influencing animal welfare, immunity, and thus the quality of animal products. MATERIAL AND METHODS: The study used amplification-created restriction site and PCR-restriction fragment length polym...

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Autores principales: Hiller, Sonia, Kowalewska, Inga, Czerniawska-Piątkowska, Ewa, Banaszewska, Dorota
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sciendo 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10062051/
https://www.ncbi.nlm.nih.gov/pubmed/37008775
http://dx.doi.org/10.2478/jvetres-2023-0018
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author Hiller, Sonia
Kowalewska, Inga
Czerniawska-Piątkowska, Ewa
Banaszewska, Dorota
author_facet Hiller, Sonia
Kowalewska, Inga
Czerniawska-Piątkowska, Ewa
Banaszewska, Dorota
author_sort Hiller, Sonia
collection PubMed
description INTRODUCTION: Antimicrobial peptides, including cathelicidins, play a significant role in farm animals, influencing animal welfare, immunity, and thus the quality of animal products. MATERIAL AND METHODS: The study used amplification-created restriction site and PCR-restriction fragment length polymorphism to analyse single nucleotide polymorphisms of the CATHL7 gene encoding the BMAP-34 protein in cattle, at positions 2,383 G > C and 2,468 G > C. The material was collected from 279 Polish Black-and-White Holstein-Friesian dairy cows. RESULTS: There were statistically significant differences between milk performance parameters in cows with the CATHL7/HhaI and CATHL7/HinfI genotypes. In the case of the CATHL7/HhaI polymorphism, the highest milk yield and protein and lactose content and the lowest somatic cell count in milk were observed for the CC genotype, while the fat content was the highest in milk from cows with the GG genotype. In the case of the CATHL7/HinfI polymorphism, the highest protein and lactose content in milk was observed for the CC genotype. CONCLUSION: The results were statistically significant, which suggests that the search for relationships can be continued, and that the results can be used to improve selection programmes supporting dairy farming.
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spelling pubmed-100620512023-03-31 Analysis of the Effect of Polymorphisms within the CATHL7 Gene on Dairy Performance Parameters Hiller, Sonia Kowalewska, Inga Czerniawska-Piątkowska, Ewa Banaszewska, Dorota J Vet Res Research Articles INTRODUCTION: Antimicrobial peptides, including cathelicidins, play a significant role in farm animals, influencing animal welfare, immunity, and thus the quality of animal products. MATERIAL AND METHODS: The study used amplification-created restriction site and PCR-restriction fragment length polymorphism to analyse single nucleotide polymorphisms of the CATHL7 gene encoding the BMAP-34 protein in cattle, at positions 2,383 G > C and 2,468 G > C. The material was collected from 279 Polish Black-and-White Holstein-Friesian dairy cows. RESULTS: There were statistically significant differences between milk performance parameters in cows with the CATHL7/HhaI and CATHL7/HinfI genotypes. In the case of the CATHL7/HhaI polymorphism, the highest milk yield and protein and lactose content and the lowest somatic cell count in milk were observed for the CC genotype, while the fat content was the highest in milk from cows with the GG genotype. In the case of the CATHL7/HinfI polymorphism, the highest protein and lactose content in milk was observed for the CC genotype. CONCLUSION: The results were statistically significant, which suggests that the search for relationships can be continued, and that the results can be used to improve selection programmes supporting dairy farming. Sciendo 2023-03-28 /pmc/articles/PMC10062051/ /pubmed/37008775 http://dx.doi.org/10.2478/jvetres-2023-0018 Text en © 2023 S. Hiller et al., published by Sciendo https://creativecommons.org/licenses/by-nc-nd/3.0/This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.
spellingShingle Research Articles
Hiller, Sonia
Kowalewska, Inga
Czerniawska-Piątkowska, Ewa
Banaszewska, Dorota
Analysis of the Effect of Polymorphisms within the CATHL7 Gene on Dairy Performance Parameters
title Analysis of the Effect of Polymorphisms within the CATHL7 Gene on Dairy Performance Parameters
title_full Analysis of the Effect of Polymorphisms within the CATHL7 Gene on Dairy Performance Parameters
title_fullStr Analysis of the Effect of Polymorphisms within the CATHL7 Gene on Dairy Performance Parameters
title_full_unstemmed Analysis of the Effect of Polymorphisms within the CATHL7 Gene on Dairy Performance Parameters
title_short Analysis of the Effect of Polymorphisms within the CATHL7 Gene on Dairy Performance Parameters
title_sort analysis of the effect of polymorphisms within the cathl7 gene on dairy performance parameters
topic Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10062051/
https://www.ncbi.nlm.nih.gov/pubmed/37008775
http://dx.doi.org/10.2478/jvetres-2023-0018
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