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Evaluation of changes in ocular surface disease index score and meibomian gland parameters in primary pterygium

BACKGROUND: Pterygium is a commonly occurring ocular pathology, characterized by a benign proliferation of conjunctiva which extends onto the corneal surface. Abnormal tear film and meibomian gland (MG) dysfunction have been linked to pterygium development. AIMS: This study was done to evaluate the...

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Autores principales: Mathur, Radha, Ashish, Chander, Suman, Rastogi Priye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10062065/
https://www.ncbi.nlm.nih.gov/pubmed/37007250
http://dx.doi.org/10.4103/ojo.ojo_71_22
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author Mathur, Radha
Ashish, Chander
Suman, Rastogi Priye
author_facet Mathur, Radha
Ashish, Chander
Suman, Rastogi Priye
author_sort Mathur, Radha
collection PubMed
description BACKGROUND: Pterygium is a commonly occurring ocular pathology, characterized by a benign proliferation of conjunctiva which extends onto the corneal surface. Abnormal tear film and meibomian gland (MG) dysfunction have been linked to pterygium development. AIMS: This study was done to evaluate the changes taking place in the Ocular Surface Disease Index (OSDI) score and other tear film parameters with MG parameters in patients of primary pterygium as well as evaluation of the relation between them in pterygium. SETTINGS AND DESIGN: This was a case–control study, done in a tertiary care hospital in North India. MATERIALS AND METHODS: Patients presenting to the ophthalmology outpatient department with a diagnosis of pterygium were enrolled in the pterygium study group along with their gender- and age-matched controls. Both groups were evaluated for OSDI score and other tear films and MG parameters were compared. STATISTICAL ANALYSIS USED: The results were analyzed using SPSS version 24.0. A P < 0.05 was considered statistically significant. RESULTS: The OSDI score was significant among the study groups with a P = 0.006 and the MG parameters of MG expression score, lid margin abnormality, and meiboscore were also significant with a P = 0.002, 0.002, and < 0.01, respectively. CONCLUSIONS: There is a positive association between pterygium, tear film abnormality, and MG disease (MGD). A strong association was also established between MGD and dry eye. Any alteration in one will aggravate the other.
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spelling pubmed-100620652023-03-31 Evaluation of changes in ocular surface disease index score and meibomian gland parameters in primary pterygium Mathur, Radha Ashish, Chander Suman, Rastogi Priye Oman J Ophthalmol Original Article BACKGROUND: Pterygium is a commonly occurring ocular pathology, characterized by a benign proliferation of conjunctiva which extends onto the corneal surface. Abnormal tear film and meibomian gland (MG) dysfunction have been linked to pterygium development. AIMS: This study was done to evaluate the changes taking place in the Ocular Surface Disease Index (OSDI) score and other tear film parameters with MG parameters in patients of primary pterygium as well as evaluation of the relation between them in pterygium. SETTINGS AND DESIGN: This was a case–control study, done in a tertiary care hospital in North India. MATERIALS AND METHODS: Patients presenting to the ophthalmology outpatient department with a diagnosis of pterygium were enrolled in the pterygium study group along with their gender- and age-matched controls. Both groups were evaluated for OSDI score and other tear films and MG parameters were compared. STATISTICAL ANALYSIS USED: The results were analyzed using SPSS version 24.0. A P < 0.05 was considered statistically significant. RESULTS: The OSDI score was significant among the study groups with a P = 0.006 and the MG parameters of MG expression score, lid margin abnormality, and meiboscore were also significant with a P = 0.002, 0.002, and < 0.01, respectively. CONCLUSIONS: There is a positive association between pterygium, tear film abnormality, and MG disease (MGD). A strong association was also established between MGD and dry eye. Any alteration in one will aggravate the other. Wolters Kluwer - Medknow 2023-02-21 /pmc/articles/PMC10062065/ /pubmed/37007250 http://dx.doi.org/10.4103/ojo.ojo_71_22 Text en Copyright: © 2023 Oman Ophthalmic Society https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Mathur, Radha
Ashish, Chander
Suman, Rastogi Priye
Evaluation of changes in ocular surface disease index score and meibomian gland parameters in primary pterygium
title Evaluation of changes in ocular surface disease index score and meibomian gland parameters in primary pterygium
title_full Evaluation of changes in ocular surface disease index score and meibomian gland parameters in primary pterygium
title_fullStr Evaluation of changes in ocular surface disease index score and meibomian gland parameters in primary pterygium
title_full_unstemmed Evaluation of changes in ocular surface disease index score and meibomian gland parameters in primary pterygium
title_short Evaluation of changes in ocular surface disease index score and meibomian gland parameters in primary pterygium
title_sort evaluation of changes in ocular surface disease index score and meibomian gland parameters in primary pterygium
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10062065/
https://www.ncbi.nlm.nih.gov/pubmed/37007250
http://dx.doi.org/10.4103/ojo.ojo_71_22
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