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Diffuse large cell lymphoma of the lacrimal sac may mimic as acute dacryocystitis
A 36-year-old male patient presented with a firm swelling in the left lacrimal sac region with a history of recurrent episodes of acute dacryocystitis, which partly resolved with systemic antibiotics. Computed tomography showed diffuse soft tissue mass without bony erosion in the same area. Incision...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10062069/ https://www.ncbi.nlm.nih.gov/pubmed/37007254 http://dx.doi.org/10.4103/ojo.ojo_304_21 |
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author | Roy, Soma Rani Nuruddin, Murtuza Hoque, Fahmida |
author_facet | Roy, Soma Rani Nuruddin, Murtuza Hoque, Fahmida |
author_sort | Roy, Soma Rani |
collection | PubMed |
description | A 36-year-old male patient presented with a firm swelling in the left lacrimal sac region with a history of recurrent episodes of acute dacryocystitis, which partly resolved with systemic antibiotics. Computed tomography showed diffuse soft tissue mass without bony erosion in the same area. Incisional biopsy confirmed diffuse large cell lymphoma of non-Hodgkin's type by histopathology and immunohistochemistry. Oncologists did not detect systemic involvement, and the patient received six cycles of cyclophosphamide, hydroxydaunorubicin, oncovin, and prednisolone (CHOP). Epiphora was resolved, and no recurrence of the lesion was seen with subsequent dacryocystorhinostomy with intubation and was in good health for up to 3 years of follow-up. Although primary lacrimal sac lymphoma is a rare entity, high suspicion, and prompt action in atypical cases can save lives from aggressive diffuse large cell lymphoma. |
format | Online Article Text |
id | pubmed-10062069 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-100620692023-03-31 Diffuse large cell lymphoma of the lacrimal sac may mimic as acute dacryocystitis Roy, Soma Rani Nuruddin, Murtuza Hoque, Fahmida Oman J Ophthalmol Case Report A 36-year-old male patient presented with a firm swelling in the left lacrimal sac region with a history of recurrent episodes of acute dacryocystitis, which partly resolved with systemic antibiotics. Computed tomography showed diffuse soft tissue mass without bony erosion in the same area. Incisional biopsy confirmed diffuse large cell lymphoma of non-Hodgkin's type by histopathology and immunohistochemistry. Oncologists did not detect systemic involvement, and the patient received six cycles of cyclophosphamide, hydroxydaunorubicin, oncovin, and prednisolone (CHOP). Epiphora was resolved, and no recurrence of the lesion was seen with subsequent dacryocystorhinostomy with intubation and was in good health for up to 3 years of follow-up. Although primary lacrimal sac lymphoma is a rare entity, high suspicion, and prompt action in atypical cases can save lives from aggressive diffuse large cell lymphoma. Wolters Kluwer - Medknow 2023-02-21 /pmc/articles/PMC10062069/ /pubmed/37007254 http://dx.doi.org/10.4103/ojo.ojo_304_21 Text en Copyright: © 2023 Oman Ophthalmic Society https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Case Report Roy, Soma Rani Nuruddin, Murtuza Hoque, Fahmida Diffuse large cell lymphoma of the lacrimal sac may mimic as acute dacryocystitis |
title | Diffuse large cell lymphoma of the lacrimal sac may mimic as acute dacryocystitis |
title_full | Diffuse large cell lymphoma of the lacrimal sac may mimic as acute dacryocystitis |
title_fullStr | Diffuse large cell lymphoma of the lacrimal sac may mimic as acute dacryocystitis |
title_full_unstemmed | Diffuse large cell lymphoma of the lacrimal sac may mimic as acute dacryocystitis |
title_short | Diffuse large cell lymphoma of the lacrimal sac may mimic as acute dacryocystitis |
title_sort | diffuse large cell lymphoma of the lacrimal sac may mimic as acute dacryocystitis |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10062069/ https://www.ncbi.nlm.nih.gov/pubmed/37007254 http://dx.doi.org/10.4103/ojo.ojo_304_21 |
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