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Reticular corneal epithelial edema with topical netarsudil

Rho-associated protein kinase inhibitor (ROCK) therapy for corneal endothelial dysfunction or damage other than glaucoma has been reported with few ocular side effects. We report reticular epithelial edema (REE) with netarsudil (0.02%) therapy in four cases with different clinical scenarios (three c...

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Detalles Bibliográficos
Autores principales: Parmar, Dipali P., Bhole, Pradnya K., Garde, Pawan V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10062072/
https://www.ncbi.nlm.nih.gov/pubmed/37007228
http://dx.doi.org/10.4103/ojo.ojo_2_22
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author Parmar, Dipali P.
Bhole, Pradnya K.
Garde, Pawan V.
author_facet Parmar, Dipali P.
Bhole, Pradnya K.
Garde, Pawan V.
author_sort Parmar, Dipali P.
collection PubMed
description Rho-associated protein kinase inhibitor (ROCK) therapy for corneal endothelial dysfunction or damage other than glaucoma has been reported with few ocular side effects. We report reticular epithelial edema (REE) with netarsudil (0.02%) therapy in four cases with different clinical scenarios (three cases with corneal transplant and one case postcataract extraction). REE developed in all cases variably and cleared on cessation of netarsudil in three cases. One case was continued on netarsudil due to REE sparing the visual axis with no active ocular complaints. Partial clearance of stromal edema observed in all cases was correlated clinically to visual acuity considering existing comorbidities in an individual case.
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spelling pubmed-100620722023-03-31 Reticular corneal epithelial edema with topical netarsudil Parmar, Dipali P. Bhole, Pradnya K. Garde, Pawan V. Oman J Ophthalmol Case Series Rho-associated protein kinase inhibitor (ROCK) therapy for corneal endothelial dysfunction or damage other than glaucoma has been reported with few ocular side effects. We report reticular epithelial edema (REE) with netarsudil (0.02%) therapy in four cases with different clinical scenarios (three cases with corneal transplant and one case postcataract extraction). REE developed in all cases variably and cleared on cessation of netarsudil in three cases. One case was continued on netarsudil due to REE sparing the visual axis with no active ocular complaints. Partial clearance of stromal edema observed in all cases was correlated clinically to visual acuity considering existing comorbidities in an individual case. Wolters Kluwer - Medknow 2023-02-21 /pmc/articles/PMC10062072/ /pubmed/37007228 http://dx.doi.org/10.4103/ojo.ojo_2_22 Text en Copyright: © 2023 Oman Ophthalmic Society https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Series
Parmar, Dipali P.
Bhole, Pradnya K.
Garde, Pawan V.
Reticular corneal epithelial edema with topical netarsudil
title Reticular corneal epithelial edema with topical netarsudil
title_full Reticular corneal epithelial edema with topical netarsudil
title_fullStr Reticular corneal epithelial edema with topical netarsudil
title_full_unstemmed Reticular corneal epithelial edema with topical netarsudil
title_short Reticular corneal epithelial edema with topical netarsudil
title_sort reticular corneal epithelial edema with topical netarsudil
topic Case Series
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10062072/
https://www.ncbi.nlm.nih.gov/pubmed/37007228
http://dx.doi.org/10.4103/ojo.ojo_2_22
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