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Immunity to Seasonal Coronavirus Spike Proteins Does Not Protect from SARS-CoV-2 Challenge in a Mouse Model but Has No Detrimental Effect on Protection Mediated by COVID-19 mRNA Vaccination

Seasonal coronaviruses have been circulating widely in the human population for many years. With increasing age, humans are more likely to have been exposed to these viruses and to have developed immunity against them. It has been hypothesized that this immunity to seasonal coronaviruses may provide...

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Detalles Bibliográficos
Autores principales: Amanat, Fatima, Clark, Jordan, Carreño, Juan Manuel, Strohmeier, Shirin, Yellin, Temima, Meade, Philip S., Bhavsar, Disha, Muramatsu, Hiromi, Sun, Weina, Coughlan, Lynda, Pardi, Norbert, Krammer, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10062180/
https://www.ncbi.nlm.nih.gov/pubmed/36779758
http://dx.doi.org/10.1128/jvi.01664-22