Analyses of thymocyte commitment to regulatory T cell lineage in thymus of healthy subjects and patients with 22q11.2 deletion syndrome

The Chromosome 22q11.2 deletion syndrome (22q11.2DS) results in an inborn error of immunity due to defective thymic organogenesis. Immunological abnormalities in 22q11.2DS patients are thymic hypoplasia, reduced output of T lymphocytes by the thymus, immunodeficiency and increased incidence of autoi...

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Detalles Bibliográficos
Autores principales: Borna, Simon, Dejene, Beruh, Lakshmanan, Uma, Schulze, Janika, Weinberg, Kenneth, Bacchetta, Rosa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10062184/
https://www.ncbi.nlm.nih.gov/pubmed/37006241
http://dx.doi.org/10.3389/fimmu.2023.1088059

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