The L1 cell adhesion molecule constrains dendritic spine density in pyramidal neurons of the mouse cerebral cortex

A novel function for the L1 cell adhesion molecule, which binds the actin adaptor protein Ankyrin was identified in constraining dendritic spine density on pyramidal neurons in the mouse neocortex. In an L1-null mouse mutant increased spine density was observed on apical but not basal dendrites of p...

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Detalles Bibliográficos
Autores principales: Murphy, Kelsey E., Wade, Sarah D., Sperringer, Justin E., Mohan, Vishwa, Duncan, Bryce W., Zhang, Erin Y., Pak, Yubin, Lutz, David, Schachner, Melitta, Maness, Patricia F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10062527/
https://www.ncbi.nlm.nih.gov/pubmed/37007644
http://dx.doi.org/10.3389/fnana.2023.1111525

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