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The role of data imbalance bias in the prediction of protein stability change upon mutation
There is a controversy over what causes the low robustness of some programs for predicting protein stability change upon mutation. Some researchers suggested that low-quality data and insufficiently informative features are the primary reasons, while others attributed the problem largely to a bias c...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10062539/ https://www.ncbi.nlm.nih.gov/pubmed/36996153 http://dx.doi.org/10.1371/journal.pone.0283727 |