Natural bioactive compounds in Alzheimer's disease: From the perspective of type 3 diabetes mellitus

There is a close relationship between Alzheimer's disease (AD) and diabetes mellitus (DM), and the link between the two is often referred to as type 3 diabetes mellitus (T3DM). Many natural bioactive compounds have shown the potential to treat AD and diabetes. We mainly review the polyphenols r...

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Autores principales: Huang, Juan, Huang, Nanqu, Mao, Qianhua, Shi, Jingshan, Qiu, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Aging Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10062602/
https://www.ncbi.nlm.nih.gov/pubmed/37009462
http://dx.doi.org/10.3389/fnagi.2023.1130253
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author Huang, Juan
Huang, Nanqu
Mao, Qianhua
Shi, Jingshan
Qiu, Yu
author_facet Huang, Juan
Huang, Nanqu
Mao, Qianhua
Shi, Jingshan
Qiu, Yu
author_sort Huang, Juan
collection PubMed
description There is a close relationship between Alzheimer's disease (AD) and diabetes mellitus (DM), and the link between the two is often referred to as type 3 diabetes mellitus (T3DM). Many natural bioactive compounds have shown the potential to treat AD and diabetes. We mainly review the polyphenols represented by resveratrol (RES) and proanthocyanidins (PCs) and alkaloids represented by berberine (BBR) and Dendrobium nobile Lindl. alkaloids (DNLA) from the perspective of T3DM to review the neuroprotective effects and molecular mechanisms of natural compounds in AD.
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spelling pubmed-100626022023-03-31 Natural bioactive compounds in Alzheimer's disease: From the perspective of type 3 diabetes mellitus Huang, Juan Huang, Nanqu Mao, Qianhua Shi, Jingshan Qiu, Yu Front Aging Neurosci Aging Neuroscience There is a close relationship between Alzheimer's disease (AD) and diabetes mellitus (DM), and the link between the two is often referred to as type 3 diabetes mellitus (T3DM). Many natural bioactive compounds have shown the potential to treat AD and diabetes. We mainly review the polyphenols represented by resveratrol (RES) and proanthocyanidins (PCs) and alkaloids represented by berberine (BBR) and Dendrobium nobile Lindl. alkaloids (DNLA) from the perspective of T3DM to review the neuroprotective effects and molecular mechanisms of natural compounds in AD. Frontiers Media S.A. 2023-03-16 /pmc/articles/PMC10062602/ /pubmed/37009462 http://dx.doi.org/10.3389/fnagi.2023.1130253 Text en Copyright © 2023 Huang, Huang, Mao, Shi and Qiu. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Aging Neuroscience
Huang, Juan
Huang, Nanqu
Mao, Qianhua
Shi, Jingshan
Qiu, Yu
Natural bioactive compounds in Alzheimer's disease: From the perspective of type 3 diabetes mellitus
title Natural bioactive compounds in Alzheimer's disease: From the perspective of type 3 diabetes mellitus
title_full Natural bioactive compounds in Alzheimer's disease: From the perspective of type 3 diabetes mellitus
title_fullStr Natural bioactive compounds in Alzheimer's disease: From the perspective of type 3 diabetes mellitus
title_full_unstemmed Natural bioactive compounds in Alzheimer's disease: From the perspective of type 3 diabetes mellitus
title_short Natural bioactive compounds in Alzheimer's disease: From the perspective of type 3 diabetes mellitus
title_sort natural bioactive compounds in alzheimer's disease: from the perspective of type 3 diabetes mellitus
topic Aging Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10062602/
https://www.ncbi.nlm.nih.gov/pubmed/37009462
http://dx.doi.org/10.3389/fnagi.2023.1130253
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