Exhausted intratumoral Vδ2(−) γδ T cells in human kidney cancer retain effector function

Gamma delta (γδ) T cells reside within human tissues including tumors, but their function in mediating antitumor responses to immune checkpoint inhibition is unknown. Here we show that kidney cancers are infiltrated by Vδ2(−) γδ T cells, with equivalent representation of Vδ1(+) and Vδ1(−) cells, tha...

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Detalles Bibliográficos
Autores principales: Rancan, Chiara, Arias-Badia, Marcel, Dogra, Pranay, Chen, Brandon, Aran, Dvir, Yang, Hai, Luong, Diamond, Ilano, Arielle, Li, Jacky, Chang, Hewitt, Kwek, Serena S., Zhang, Li, Lanier, Lewis L., Meng, Maxwell V., Farber, Donna L., Fong, Lawrence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10063448/
https://www.ncbi.nlm.nih.gov/pubmed/36928415
http://dx.doi.org/10.1038/s41590-023-01448-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10063448/
https://www.ncbi.nlm.nih.gov/pubmed/36928415
http://dx.doi.org/10.1038/s41590-023-01448-7

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