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Brain disorders: Impact of mild SARS-CoV-2 may shrink several parts of the brain
Coronavirus (COVID-19) is a highly infectious respiratory infection discovered in Wuhan, China, in December 2019. As a result of the pandemic, several individuals have experienced life-threatening diseases, the loss of loved ones, lockdowns, isolation, an increase in unemployment, and household conf...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10063523/ https://www.ncbi.nlm.nih.gov/pubmed/37004892 http://dx.doi.org/10.1016/j.neubiorev.2023.105150 |
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author | Kumar, Puranam Revanth Shilpa, B. Jha, Rajesh Kumar |
author_facet | Kumar, Puranam Revanth Shilpa, B. Jha, Rajesh Kumar |
author_sort | Kumar, Puranam Revanth |
collection | PubMed |
description | Coronavirus (COVID-19) is a highly infectious respiratory infection discovered in Wuhan, China, in December 2019. As a result of the pandemic, several individuals have experienced life-threatening diseases, the loss of loved ones, lockdowns, isolation, an increase in unemployment, and household conflict. Moreover, COVID-19 may cause direct brain injury via encephalopathy. The long-term impacts of this virus on mental health and brain function need to be analysed by researchers in the coming years. This article aims to describe the prolonged neurological clinical consequences related to brain changes in people with mild COVID-19 infection. When compared to a control group, people those who tested positive for COVID-19 had more brain shrinkage, grey matter shrinkage, and tissue damage. The damage occurs predominantly in areas of the brain that are associated with odour, ambiguity, strokes, reduced attention, headaches, sensory abnormalities, depression, and mental abilities for few months after the first infection. Therefore, in patients after a severe clinical condition of COVID-19, a deepening of persistent neurological signs is necessary. |
format | Online Article Text |
id | pubmed-10063523 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Elsevier Ltd. |
record_format | MEDLINE/PubMed |
spelling | pubmed-100635232023-03-31 Brain disorders: Impact of mild SARS-CoV-2 may shrink several parts of the brain Kumar, Puranam Revanth Shilpa, B. Jha, Rajesh Kumar Neurosci Biobehav Rev Review Article Coronavirus (COVID-19) is a highly infectious respiratory infection discovered in Wuhan, China, in December 2019. As a result of the pandemic, several individuals have experienced life-threatening diseases, the loss of loved ones, lockdowns, isolation, an increase in unemployment, and household conflict. Moreover, COVID-19 may cause direct brain injury via encephalopathy. The long-term impacts of this virus on mental health and brain function need to be analysed by researchers in the coming years. This article aims to describe the prolonged neurological clinical consequences related to brain changes in people with mild COVID-19 infection. When compared to a control group, people those who tested positive for COVID-19 had more brain shrinkage, grey matter shrinkage, and tissue damage. The damage occurs predominantly in areas of the brain that are associated with odour, ambiguity, strokes, reduced attention, headaches, sensory abnormalities, depression, and mental abilities for few months after the first infection. Therefore, in patients after a severe clinical condition of COVID-19, a deepening of persistent neurological signs is necessary. Elsevier Ltd. 2023-06 2023-03-31 /pmc/articles/PMC10063523/ /pubmed/37004892 http://dx.doi.org/10.1016/j.neubiorev.2023.105150 Text en © 2023 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Review Article Kumar, Puranam Revanth Shilpa, B. Jha, Rajesh Kumar Brain disorders: Impact of mild SARS-CoV-2 may shrink several parts of the brain |
title | Brain disorders: Impact of mild SARS-CoV-2 may shrink several parts of the brain |
title_full | Brain disorders: Impact of mild SARS-CoV-2 may shrink several parts of the brain |
title_fullStr | Brain disorders: Impact of mild SARS-CoV-2 may shrink several parts of the brain |
title_full_unstemmed | Brain disorders: Impact of mild SARS-CoV-2 may shrink several parts of the brain |
title_short | Brain disorders: Impact of mild SARS-CoV-2 may shrink several parts of the brain |
title_sort | brain disorders: impact of mild sars-cov-2 may shrink several parts of the brain |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10063523/ https://www.ncbi.nlm.nih.gov/pubmed/37004892 http://dx.doi.org/10.1016/j.neubiorev.2023.105150 |
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