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Brain disorders: Impact of mild SARS-CoV-2 may shrink several parts of the brain

Coronavirus (COVID-19) is a highly infectious respiratory infection discovered in Wuhan, China, in December 2019. As a result of the pandemic, several individuals have experienced life-threatening diseases, the loss of loved ones, lockdowns, isolation, an increase in unemployment, and household conf...

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Detalles Bibliográficos
Autores principales: Kumar, Puranam Revanth, Shilpa, B., Jha, Rajesh Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10063523/
https://www.ncbi.nlm.nih.gov/pubmed/37004892
http://dx.doi.org/10.1016/j.neubiorev.2023.105150
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author Kumar, Puranam Revanth
Shilpa, B.
Jha, Rajesh Kumar
author_facet Kumar, Puranam Revanth
Shilpa, B.
Jha, Rajesh Kumar
author_sort Kumar, Puranam Revanth
collection PubMed
description Coronavirus (COVID-19) is a highly infectious respiratory infection discovered in Wuhan, China, in December 2019. As a result of the pandemic, several individuals have experienced life-threatening diseases, the loss of loved ones, lockdowns, isolation, an increase in unemployment, and household conflict. Moreover, COVID-19 may cause direct brain injury via encephalopathy. The long-term impacts of this virus on mental health and brain function need to be analysed by researchers in the coming years. This article aims to describe the prolonged neurological clinical consequences related to brain changes in people with mild COVID-19 infection. When compared to a control group, people those who tested positive for COVID-19 had more brain shrinkage, grey matter shrinkage, and tissue damage. The damage occurs predominantly in areas of the brain that are associated with odour, ambiguity, strokes, reduced attention, headaches, sensory abnormalities, depression, and mental abilities for few months after the first infection. Therefore, in patients after a severe clinical condition of COVID-19, a deepening of persistent neurological signs is necessary.
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spelling pubmed-100635232023-03-31 Brain disorders: Impact of mild SARS-CoV-2 may shrink several parts of the brain Kumar, Puranam Revanth Shilpa, B. Jha, Rajesh Kumar Neurosci Biobehav Rev Review Article Coronavirus (COVID-19) is a highly infectious respiratory infection discovered in Wuhan, China, in December 2019. As a result of the pandemic, several individuals have experienced life-threatening diseases, the loss of loved ones, lockdowns, isolation, an increase in unemployment, and household conflict. Moreover, COVID-19 may cause direct brain injury via encephalopathy. The long-term impacts of this virus on mental health and brain function need to be analysed by researchers in the coming years. This article aims to describe the prolonged neurological clinical consequences related to brain changes in people with mild COVID-19 infection. When compared to a control group, people those who tested positive for COVID-19 had more brain shrinkage, grey matter shrinkage, and tissue damage. The damage occurs predominantly in areas of the brain that are associated with odour, ambiguity, strokes, reduced attention, headaches, sensory abnormalities, depression, and mental abilities for few months after the first infection. Therefore, in patients after a severe clinical condition of COVID-19, a deepening of persistent neurological signs is necessary. Elsevier Ltd. 2023-06 2023-03-31 /pmc/articles/PMC10063523/ /pubmed/37004892 http://dx.doi.org/10.1016/j.neubiorev.2023.105150 Text en © 2023 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Review Article
Kumar, Puranam Revanth
Shilpa, B.
Jha, Rajesh Kumar
Brain disorders: Impact of mild SARS-CoV-2 may shrink several parts of the brain
title Brain disorders: Impact of mild SARS-CoV-2 may shrink several parts of the brain
title_full Brain disorders: Impact of mild SARS-CoV-2 may shrink several parts of the brain
title_fullStr Brain disorders: Impact of mild SARS-CoV-2 may shrink several parts of the brain
title_full_unstemmed Brain disorders: Impact of mild SARS-CoV-2 may shrink several parts of the brain
title_short Brain disorders: Impact of mild SARS-CoV-2 may shrink several parts of the brain
title_sort brain disorders: impact of mild sars-cov-2 may shrink several parts of the brain
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10063523/
https://www.ncbi.nlm.nih.gov/pubmed/37004892
http://dx.doi.org/10.1016/j.neubiorev.2023.105150
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