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Durable responses in patients with HER2+ breast cancer and leptomeningeal metastases treated with trastuzumab deruxtecan

Leptomeningeal metastases (LM) are a devastating complication of HER2 + metastatic breast cancer (MBC), with no effective treatments. In a case series of 8 patients with heavily pretreated HER2 + MBC and progressing LM, all 8 patients (100%) derived clinical benefit from Trastuzumab deruxtecan (TDXd...

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Detalles Bibliográficos
Autores principales:	Alder, Laura, Trapani, Dario, Bradbury, Claire, Van Swearingen, Amanda E. D., Tolaney, Sara M., Khasraw, Mustafa, Anders, Carey K., Lascola, Christopher D., Hsu, Liangge, Lin, Nancy U., Sammons, Sarah
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Brief Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10063529/ https://www.ncbi.nlm.nih.gov/pubmed/36997605 http://dx.doi.org/10.1038/s41523-023-00519-0

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