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Turning universal O into rare Bombay type blood

Red blood cell antigens play critical roles in blood transfusion since donor incompatibilities can be lethal. Recipients with the rare total deficiency in H antigen, the O(h) Bombay phenotype, can only be transfused with group O(h) blood to avoid serious transfusion reactions. We discover FucOB from...

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Detalles Bibliográficos
Autores principales: Anso, Itxaso, Naegeli, Andreas, Cifuente, Javier O., Orrantia, Ane, Andersson, Erica, Zenarruzabeitia, Olatz, Moraleda-Montoya, Alicia, García-Alija, Mikel, Corzana, Francisco, Del Orbe, Rafael A., Borrego, Francisco, Trastoy, Beatriz, Sjögren, Jonathan, Guerin, Marcelo E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10063614/
https://www.ncbi.nlm.nih.gov/pubmed/36997505
http://dx.doi.org/10.1038/s41467-023-37324-z