Cargando…

Enhanced mitochondrial oxidative metabolism in peripheral blood mononuclear cells is associated with fatty liver in obese young adults

Systemic inflammation underlies the association between obesity and nonalcoholic fatty liver disease (NAFLD). Here, we investigated functional changes in leukocytes’ mitochondria in obese individuals and their associations with NAFLD. We analyzed 14 obese male Japanese university students whose body...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shirakawa, Ryosuke, Nakajima, Takayuki, Yoshimura, Aya, Kawahara, Yukako, Orito, Chieko, Yamane, Miwako, Handa, Haruka, Takada, Shingo, Furihata, Takaaki, Fukushima, Arata, Ishimori, Naoki, Nakagawa, Masao, Yokota, Isao, Sabe, Hisataka, Hashino, Satoshi, Kinugawa, Shintaro, Yokota, Takashi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10063628/ https://www.ncbi.nlm.nih.gov/pubmed/36997629 http://dx.doi.org/10.1038/s41598-023-32549-w

Ejemplares similares

Cross-disease communication between cancer and heart failure provides a rational approach to prevention and treatment of both diseases
por: Takada, Shingo, et al.
Publicado: (2022)

Mitochondrial reactive oxygen species generation in blood cells is associated with disease severity and exercise intolerance in heart failure patients
por: Shirakawa, Ryosuke, et al.
Publicado: (2019)

Mitochondrial respiration of complex II is not lower than that of complex I in mouse skeletal muscle
por: Maekawa, Satoshi, et al.
Publicado: (2019)

Succinyl-CoA-based energy metabolism dysfunction in chronic heart failure
por: Takada, Shingo, et al.
Publicado: (2022)

Angiotensin-converting-enzyme inhibitor prevents skeletal muscle fibrosis in myocardial infarction mice
por: Kakutani, Naoya, et al.
Publicado: (2020)

The AppCare-HF randomized clinical trial: a feasibility study of a novel self-care support mobile app for individuals with chronic heart failure
por: Yokota, Takashi, et al.
Publicado: (2023)

Cardiac-specific loss of mitoNEET expression is linked with age-related heart failure
por: Furihata, Takaaki, et al.
Publicado: (2021)

Premedication with pioglitazone prevents doxorubicin-induced left ventricular dysfunction in mice
por: Furihata, Takaaki, et al.
Publicado: (2021)

Deletion of NAD(P)H Oxidase 2 Prevents Angiotensin II-Induced Skeletal Muscle Atrophy
por: Kadoguchi, Tomoyasu, et al.
Publicado: (2018)

Abnormalities of Skeletal Muscle, Adipocyte Tissue, and Lipid Metabolism in Heart Failure: Practical Therapeutic Targets
por: Takada, Shingo, et al.
Publicado: (2020)

Sesamin prevents decline in exercise capacity and impairment of skeletal muscle mitochondrial function in mice with high‐fat diet‐induced diabetes
por: Takada, Shingo, et al.
Publicado: (2015)

Protein acetylation in skeletal muscle mitochondria is involved in impaired fatty acid oxidation and exercise intolerance in heart failure
por: Tsuda, Masaya, et al.
Publicado: (2018)

Clinical Impact and Associated Factors of Delayed Ambulation in Patients With Acute Heart Failure
por: Ishikawa, Koji, et al.
Publicado: (2019)

Linoleic acid improves assembly of the CII subunit and CIII2/CIV complex of the mitochondrial oxidative phosphorylation system in heart failure
por: Maekawa, Satoshi, et al.
Publicado: (2019)

The experimental model of transition from compensated cardiac hypertrophy to failure created by transverse aortic constriction in mice
por: Furihata, Takaaki, et al.
Publicado: (2016)

Type 2 diabetes is an independent predictor of lowered peak aerobic capacity in heart failure patients with non-reduced or reduced left ventricular ejection fraction
por: Abe, Takahiro, et al.
Publicado: (2020)

Impaired mitochondrial oxidative phosphorylation capacity in epicardial adipose tissue is associated with decreased concentration of adiponectin and severity of coronary atherosclerosis
por: Nakajima, Takayuki, et al.
Publicado: (2019)

Association of Peripheral Total and Differential Leukocyte Counts with Obesity-Related Complications in Young Adults
por: Yoshimura, Aya, et al.
Publicado: (2015)

Impact of Inadequate Calorie Intake on Mortality and Hospitalization in Stable Patients with Chronic Heart Failure
por: Obata, Yoshikuni, et al.
Publicado: (2021)

Systemic oxidative stress is associated with lower aerobic capacity and impaired skeletal muscle energy metabolism in heart failure patients
por: Yokota, Takashi, et al.
Publicado: (2021)

Arf6 and its ZEB1-EPB41L5 mesenchymal axis are required for both mesenchymal- and amoeboid-type invasion of cancer cells
por: Handa, Haruka, et al.
Publicado: (2017)

Pioglitazone improves whole‐body aerobic capacity and skeletal muscle energy metabolism in patients with metabolic syndrome
por: Yokota, Takashi, et al.
Publicado: (2017)

Epithelial-specific histone modification of the miR-96/182 locus targeting AMAP1 mRNA predisposes p53 to suppress cell invasion in epithelial cells
por: Handa, Haruka, et al.
Publicado: (2018)

Progressive Mobilization Program for Patients With Acute Heart Failure Reduces Hospital Stay and Improves Clinical Outcome
por: Kakutani, Naoya, et al.
Publicado: (2019)

Oxidative stress in cardiac and skeletal muscle dysfunction associated with diabetes mellitus
por: Tsutsui, Hiroyuki, et al.
Publicado: (2011)

Necessity of p53-binding to the CDH1 locus for its expression defines two epithelial cell types differing in their integrity
por: Oikawa, Tsukasa, et al.
Publicado: (2018)

Frequent overexpression of AMAP1, an Arf6 effector in cell invasion, is characteristic of the MMTV-PyMT rather than the MMTV-Neu human breast cancer model
por: Otsuka, Yutaro, et al.
Publicado: (2018)

Inhibition of mutant KRAS-driven overexpression of ARF6 and MYC by an eIF4A inhibitor drug improves the effects of anti-PD-1 immunotherapy for pancreatic cancer
por: Hashimoto, Ari, et al.
Publicado: (2021)

Validation of Gene Therapy for Mutant Mitochondria by Delivering Mitochondrial RNA Using a MITO-Porter
por: Kawamura, Eriko, et al.
Publicado: (2020)

Engagement of Overexpressed Her2 with GEP100 Induces Autonomous Invasive Activities and Provides a Biomarker for Metastases of Lung Adenocarcinoma
por: Menju, Toshi, et al.
Publicado: (2011)

Herpes Zoster Meningitis Complicating Combined Tocilizumab and Cyclosporine Therapy for Adult-Onset Still's Disease
por: Tsurukawa, Shinichiro, et al.
Publicado: (2016)

KRAS, MYC, and ARF6: inseparable relationships cooperatively promote cancer malignancy and immune evasion
por: Sabe, Hisataka
Publicado: (2023)

Ergogenic effects of caffeine are mediated by myokines
por: Takada, Shingo, et al.
Publicado: (2022)

Effect of multiple set on intramuscular metabolic stress during low-intensity resistance exercise with blood flow restriction
por: Suga, Tadashi, et al.
Publicado: (2012)

Systemic Oxidative Stress Is Associated With Lower Aerobic Capacity and Impaired Skeletal Muscle Energy Metabolism in Patients With Metabolic Syndrome
por: Yokota, Takashi, et al.
Publicado: (2013)

Rapidly Progressive Heart Failure in a Female Carrier of Becker Muscular Dystrophy with No Skeletal Muscle Symptoms
por: Komoriyama, Hirokazu, et al.
Publicado: (2019)

Lysophosphatidic acid activates Arf6 to promote the mesenchymal malignancy of renal cancer
por: Hashimoto, Shigeru, et al.
Publicado: (2016)

Idarucizumab for Emergency Reversal of Anticoagulant Effects of Dabigatran: Interim Results of a Japanese Post-Marketing Surveillance Study
por: Yasaka, Masahiro, et al.
Publicado: (2020)

PR3-ANCA in Wegener's granulomatosis prime human mononuclear cells for enhanced activation via TLRs and NOD1/2
por: Uehara, Akiko, et al.
Publicado: (2009)

Hydrogel Heart Model with Temperature Memory Properties for Surgical Simulation
por: Maruyama, Hisataka, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_t74e27patiug630ogou61i70vp