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Type I interferon score is associated with the severity and poor prognosis in anti-MDA5 antibody-positive dermatomyositis patients

OBJECTIVES: To investigate the clinical significance of the interferon (IFN) score, especially the IFN-I score, in patients with anti-melanoma differentiation-associated gene 5 (MDA5) antibody-positive dermatomyositis (anti-MDA5(+) DM). METHODS: We enrolled 262 patients with different autoimmune dis...

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Detalles Bibliográficos
Autores principales: Qian, Jinjing, Li, Rui, Chen, Zhiwei, Cao, Zehui, Lu, Liangjing, Fu, Qiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10063972/
https://www.ncbi.nlm.nih.gov/pubmed/37006269
http://dx.doi.org/10.3389/fimmu.2023.1151695