Cargando…

Type I interferon score is associated with the severity and poor prognosis in anti-MDA5 antibody-positive dermatomyositis patients

OBJECTIVES: To investigate the clinical significance of the interferon (IFN) score, especially the IFN-I score, in patients with anti-melanoma differentiation-associated gene 5 (MDA5) antibody-positive dermatomyositis (anti-MDA5(+) DM). METHODS: We enrolled 262 patients with different autoimmune dis...

Descripción completa

Detalles Bibliográficos
Autores principales:	Qian, Jinjing, Li, Rui, Chen, Zhiwei, Cao, Zehui, Lu, Liangjing, Fu, Qiong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10063972/ https://www.ncbi.nlm.nih.gov/pubmed/37006269 http://dx.doi.org/10.3389/fimmu.2023.1151695

Ejemplares similares

Dermatomyositis With Anti-MDA5 Antibodies: Bioclinical Features, Pathogenesis and Emerging Therapies
por: Nombel, Anaïs, et al.
Publicado: (2021)

ECG Changes Through Immunosuppressive Therapy Indicate Cardiac Abnormality in Anti-MDA5 Antibody-Positive Clinically Amyopathic Dermatomyositis
por: Matsuo, Takashi, et al.
Publicado: (2022)

The clinical features and prognoses of anti-MDA5 and anti-aminoacyl-tRNA synthetase antibody double-positive dermatomyositis patients
por: Chen, Xixia, et al.
Publicado: (2022)

Machine learning for screening and predicting the risk of anti-MDA5 antibody in juvenile dermatomyositis children
por: Xue, Yuan, et al.
Publicado: (2023)

Transcriptomic profiling and longitudinal study reveal the relationship of anti-MDA5 titer and type I IFN signature in MDA5+ dermatomyositis
por: Wang, Yan, et al.
Publicado: (2023)

A novel CT scoring method predicts the prognosis of interstitial lung disease associated with anti-MDA5 positive dermatomyositis
por: Xu, Wenwen, et al.
Publicado: (2021)

Clinical Features of Dermatomyositis/Polymyositis with Anti-MDA5 Antibody Positivity
por: Chen, Qiuhe, et al.
Publicado: (2022)

Editorial: Anti-MDA5-Positive Dermatomyositis
por: Gono, Takahisa, et al.
Publicado: (2022)

Anti-MDA5 antibody-positive dermatomyositis presenting as unilateral eyelid edema
por: Chen, Lauren, et al.
Publicado: (2020)

Adrenomedullin Expression Is Associated With the Severity and Poor Prognosis of Interstitial Lung Disease in Dermatomyositis Patients
por: Ye, Lifang, et al.
Publicado: (2022)

Macrophage activation syndrome in MDA5 antibody-positive dermatomyositis and COVID-19 infection
por: Keshtkarjahromi, Marzieh, et al.
Publicado: (2021)

Ground-glass opacity score predicts the prognosis of anti-MDA5 positive dermatomyositis: a single-centre cohort study
por: Liu, Lijun, et al.
Publicado: (2023)

Different Multivariable Risk Factors for Rapid Progressive Interstitial Lung Disease in Anti-MDA5 Positive Dermatomyositis and Anti-Synthetase Syndrome
por: Zuo, Yu, et al.
Publicado: (2022)

Anti-MDA5 Antibody Linking COVID-19, Type I Interferon, and Autoimmunity: A Case Report and Systematic Literature Review
por: Tonutti, Antonio, et al.
Publicado: (2022)

hnRNPH2 as an Inhibitor of Chicken MDA5-Mediated Type I Interferon Response: Analysis Using Chicken MDA5–Host Interactome
por: Lin, Xian, et al.
Publicado: (2020)

Management of MDA-5 antibody-positive dermatomyositis with interstitial lung disease—an Auckland case series
por: Dick, Michael, et al.
Publicado: (2021)

Cutaneous Features of Anti-MDA-5 Antibody-Positive Amyopathic Dermatomyositis in a Sudanese Patient
por: Alqahtani, Nouf, et al.
Publicado: (2021)

Efficacy and safety of dose escalation of tofacitinib in refractory anti-MDA5 antibody-positive dermatomyositis
por: Ida, Tomoaki, et al.
Publicado: (2023)

Myocardial involvement is not rare in anti-melanoma differentiation-associated gene 5 antibody-positive dermatomyositis/clinically amyopathic dermatomyositis: a retrospective study
por: Zhou, Shuang, et al.
Publicado: (2022)

Anti-MDA5 Antibody-Positive Dermatomyositis Presenting with Cellulitis-Like Erythema on the Mandible as an Initial Symptom
por: Hattori, Yuki, et al.
Publicado: (2018)

Association of Cytomegalovirus Infection With Anti-MDA5 Antibody-Positive Dermatomyositis: A Prospective Cohort Study
por: Huang, Linlin, et al.
Publicado: (2021)

High incidence and mortality of Pneumocystis jirovecii infection in anti-MDA5-antibody-positive dermatomyositis: experience from a single center
por: Huang, Linlin, et al.
Publicado: (2021)

Single-cell profiling reveals distinct adaptive immune hallmarks in MDA5+ dermatomyositis with therapeutic implications
por: Ye, Yan, et al.
Publicado: (2022)

Treatment of MDA5-positive dermatomyositis complicated by gangrenous cholecystitis with tofacitinib
por: Luo, Man, et al.
Publicado: (2022)

Subcutaneous Calcinosis in a Patient with Anti-MDA5 Positive Dermatomyositis
por: Hou, Ruihong, et al.
Publicado: (2021)

Filovirus VP24 Proteins Differentially Regulate RIG-I and MDA5-Dependent Type I and III Interferon Promoter Activation
por: He, Felix B., et al.
Publicado: (2022)

Serum KL‐6 level is a prognostic marker in patients with anti‐MDA5 antibody‐positive dermatomyositis associated with interstitial lung disease
por: Ye, Yan, et al.
Publicado: (2019)

MDA5 Induces a Stronger Interferon Response than RIG-I to GCRV Infection through a Mechanism Involving the Phosphorylation and Dimerization of IRF3 and IRF7 in CIK Cells
por: Wan, Quanyuan, et al.
Publicado: (2017)

Anti-MDA5 Antibodies in a Large Mediterranean Population of Adults with Dermatomyositis
por: Labrador-Horrillo, Moises, et al.
Publicado: (2014)

Anti-MDA5 antibody-positive dermatomyositis with rapidly progressive interstitial lung disease: report of two cases
por: Mehta, Asmita A, et al.
Publicado: (2021)

Successful peficitinib addition on anti-MDA5 antibody-positive dermatomyositis refractory to triple therapy and glucocorticoid reduction
por: Oba, Yuki, et al.
Publicado: (2022)

Soluble CD206 levels correlate with disease deterioration and predict prognosis of anti‐MDA5 antibody‐positive dermatomyositis related interstitial lung disease
por: Li, Yan, et al.
Publicado: (2023)

7. Anti-MDA5 associated dermatomyositis
por: Laverty, Ursula, et al.
Publicado: (2019)

MDA5-positive dermatomyositis: an uncommon entity in Europe with variable clinical presentations
por: Parronchi, Paola, et al.
Publicado: (2015)

Seasonal Effect on Disease Onset and Presentation in Anti-MDA5 Positive Dermatomyositis
por: So, Ho, et al.
Publicado: (2022)

Analysis of Porcine RIG-I Like Receptors Revealed the Positive Regulation of RIG-I and MDA5 by LGP2
por: Li, Shuangjie, et al.
Publicado: (2021)

Clinical Features of Anti-MDA5 Antibody-positive Rapidly Progressive Interstitial Lung Disease without Signs of Dermatomyositis
por: Sakamoto, Noriho, et al.
Publicado: (2018)

Anti-MDA5 Antibody-positive Clinically Amyopathic Dermatomyositis Complicated by Unilateral Right-sided Interstitial Lung Disease
por: Kori, Mayuko, et al.
Publicado: (2020)

Complication of coronavirus disease 2019 during remission induction therapy against anti-MDA5 antibody-positive dermatomyositis
por: Kogami, Masahiro, et al.
Publicado: (2020)

Fulminant Course of Neuromyelitis Optica in a Patient With Anti-MDA5 Antibody-Positive Dermatomyositis: A Case Report
por: Kang, You-Ri, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_ua7a4hfpu5sss1huaiopeem14f