Cargando…

WGCNA combined with machine learning algorithms for analyzing key genes and immune cell infiltration in heart failure due to ischemic cardiomyopathy

BACKGROUND: Ischemic cardiomyopathy (ICM) induced heart failure (HF) is one of the most common causes of death worldwide. This study aimed to find candidate genes for ICM-HF and to identify relevant biomarkers by machine learning (ML). METHODS: The expression data of ICM-HF and normal samples were d...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kong, XiangJin, Sun, HouRong, Wei, KaiMing, Meng, LingWei, Lv, Xin, Liu, ChuanZhen, Lin, FuShun, Gu, XingHua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Cardiovascular Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10064046/ https://www.ncbi.nlm.nih.gov/pubmed/37008314 http://dx.doi.org/10.3389/fcvm.2023.1058834

Ejemplares similares

Exploration and validation of the influence of angiogenesis-related factors in aortic valve calcification
por: Kong, XiangJin, et al.
Publicado: (2023)

Single coronary ostium with obstructive hypertrophic cardiomyopathy treated using the Morrow procedure: a case report
por: Lv, Xin, et al.
Publicado: (2022)

Identification of key biomarkers of the glomerulus in focal segmental glomerulosclerosis and their relationship with immune cell infiltration based on WGCNA and the LASSO algorithm
por: Zhang, Yun Xia, et al.
Publicado: (2023)

Identification and validation of ferroptosis-related genes and immune infiltration in ischemic cardiomyopathy
por: Huang, Kai, et al.
Publicado: (2023)

Risk prediction model construction for post myocardial infarction heart failure by blood immune B cells
por: Sun, HouRong, et al.
Publicado: (2023)

Bioinformatics and Immune Infiltration Analyses Reveal the Key Pathway and Immune Cells in the Pathogenesis of Hypertrophic Cardiomyopathy
por: Zhang, Xu-Zhe, et al.
Publicado: (2021)

Identification of Critical Biomarkers and Immune Infiltration in Rheumatoid Arthritis Based on WGCNA and LASSO Algorithm
por: Jiang, Fan, et al.
Publicado: (2022)

WGCNA and molecular docking identify hub genes for cardiac aging
por: Ping, Ping, et al.
Publicado: (2023)

Modified GAN Augmentation Algorithms for the MRI-Classification of Myocardial Scar Tissue in Ischemic Cardiomyopathy
por: Sharma, Umesh C., et al.
Publicado: (2021)

Plasma Metabolomic Profiles Differentiate Patients With Dilated Cardiomyopathy and Ischemic Cardiomyopathy
por: Zhao, Junhan, et al.
Publicado: (2020)

Integrated Bioinformatics Algorithms and Experimental Validation to Explore Robust Biomarkers and Landscape of Immune Cell Infiltration in Dilated Cardiomyopathy
por: Zhang, Qingquan, et al.
Publicado: (2022)

Social Inequalities in Non-ischemic Cardiomyopathies
por: Amiya, Eisuke
Publicado: (2022)

Shared Genetic Etiology of Primary Dilated Cardiomyopathy and Ischemic Dilated Cardiomyopathy
por: Sun, Yang, et al.
Publicado: (2021)

Identification of Key Transcription Factors and Immune Infiltration Patterns Associated With Breast Cancer Prognosis Using WGCNA and Cox Regression Analysis
por: Yin, Xin, et al.
Publicado: (2021)

Identification of Biomarkers Associated with Heart Failure Caused by Idiopathic Dilated Cardiomyopathy Using WGCNA and Machine Learning Algorithms
por: Sun, Mengyi, et al.
Publicado: (2023)

Identification of hub genes and their correlation with infiltration of immune cells in MYCN positive neuroblastoma based on WGCNA and LASSO algorithm
por: Chen, Ji, et al.
Publicado: (2022)

Development and validation of risk prediction and neural network models for dilated cardiomyopathy based on WGCNA
por: Yu, Wei, et al.
Publicado: (2023)

Ferroptosis and Autophagy-Related Genes in the Pathogenesis of Ischemic Cardiomyopathy
por: Zheng, Yue, et al.
Publicado: (2022)

Identification of key genes in hepatitis B associated hepatocellular carcinoma based on WGCNA
por: Liu, Chang, et al.
Publicado: (2021)

Cardiac Shockwave Therapy – A Novel Therapy for Ischemic Cardiomyopathy?
por: Graber, Michael, et al.
Publicado: (2022)

Identification of potential biomarkers of inflammation-related genes for ischemic cardiomyopathy
por: Wang, Jianru, et al.
Publicado: (2022)

Comparative transcriptome and WGCNA reveal key genes involved in lignocellulose degradation in Sarcomyxa edulis
por: Duan, Chao, et al.
Publicado: (2022)

WGCNA Analysis of Salt-Responsive Core Transcriptome Identifies Novel Hub Genes in Rice
por: Zhu, Mingdong, et al.
Publicado: (2019)

Susceptibility Modules and Genes in Hypertrophic Cardiomyopathy by WGCNA and ceRNA Network Analysis
por: Sun, Yifan, et al.
Publicado: (2022)

Influence and risk factors of postoperative infection after surgery for ischemic cardiomyopathy
por: Wen, Bing, et al.
Publicado: (2023)

Identifying potential biomarkers for non-obstructive azoospermia using WGCNA and machine learning algorithms
por: Tang, Qizhen, et al.
Publicado: (2023)

Exploring Key Genes to Construct a Diagnosis Model of Dilated Cardiomyopathy
por: Zheng, Youyang, et al.
Publicado: (2022)

Identification of Key Pathways and Genes in the Dynamic Progression of HCC Based on WGCNA
por: Yin, Li, et al.
Publicado: (2018)

Identification of Immune-Related Key Genes in Ovarian Cancer Based on WGCNA
por: Quan, Qingli, et al.
Publicado: (2021)

Identification and verification of diagnostic biomarkers in recurrent pregnancy loss via machine learning algorithm and WGCNA
por: Wei, Changqiang, et al.
Publicado: (2023)

Weighted gene co expression network analysis (WGCNA) with key pathways and hub‐genes related to micro RNAs in ischemic stroke
por: Qu, Xiang, et al.
Publicado: (2021)

Long Non-coding RNA: A Key Regulator in the Pathogenesis of Diabetic Cardiomyopathy
por: Guo, Yaoyao, et al.
Publicado: (2021)

Identification of the core genes in Randall’s plaque of kidney stone and immune infiltration with WGCNA network
por: Yu, Lingyun, et al.
Publicado: (2023)

Identifying hub genes of calcific aortic valve disease and revealing the immune infiltration landscape based on multiple WGCNA and single-cell sequence analysis
por: Wang, Kan, et al.
Publicado: (2022)

Elevated α-hydroxybutyrate dehydrogenase is associated with in-hospital mortality in non-ischemic dilated cardiomyopathy
por: Li, Xinyi, et al.
Publicado: (2022)

Multi-omics integration to identify the genetic expression and protein signature of dilated and ischemic cardiomyopathy
por: Portokallidou, Konstantina, et al.
Publicado: (2023)

Identification of Key Modules and Hub Genes Involved in Regulating the Color of Chicken Breast Meat Using WGCNA
por: Guo, Xing, et al.
Publicado: (2023)

Identification of Key Genes and Pathways Associated with Preeclampsia by a WGCNA and an Evolutionary Approach
por: Kondoh, Kuniyo, et al.
Publicado: (2022)

Transcriptome Sequencing and WGCNA Reveal Key Genes in Response to Leaf Blight in Poplar
por: Wang, Ruiqi, et al.
Publicado: (2023)

Myocardial Scar Characterization and Future Ventricular Arrhythmia in Patients With Ischemic Cardiomyopathy and an Implantable Cardioverter-Defibrillator
por: Noordman, Alwin B. P., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_oeir7dvftj33kokhmrdos00bct