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Controversies and management of deficient mismatch repair gastrointestinal cancers in the neoadjuvant setting
High microsatellite instability (MSI-H)/deficient mismatch repair (dMMR) phenotype is a distinct molecular signature across gastrointestinal cancers characterized by high tumor mutational burden and high neoantigen load. Tumors harboring dMMR are highly immunogenic and heavily infiltrated by immune...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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SAGE Publications
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10064478/ https://www.ncbi.nlm.nih.gov/pubmed/37007634 http://dx.doi.org/10.1177/17588359231162577 |