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Controversies and management of deficient mismatch repair gastrointestinal cancers in the neoadjuvant setting

High microsatellite instability (MSI-H)/deficient mismatch repair (dMMR) phenotype is a distinct molecular signature across gastrointestinal cancers characterized by high tumor mutational burden and high neoantigen load. Tumors harboring dMMR are highly immunogenic and heavily infiltrated by immune...

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Detalles Bibliográficos
Autores principales:	Boutin, Mélina, Gill, Sharlene
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10064478/ https://www.ncbi.nlm.nih.gov/pubmed/37007634 http://dx.doi.org/10.1177/17588359231162577

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