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Reduced virulence in tigecycline-resistant Klebsiella pneumoniae caused by overexpression of ompR and down-regulation of ompK35

BACKGROUND: The development of tigecycline resistance in hypervirulent Klebsiella pneumoniae strains has resulted in decreased virulence that is associated with reduced production of capsular polysaccharides (CPS). In this study, we investigated the mechanisms that link tigecycline susceptibility to...

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Detalles Bibliográficos
Autores principales:	Park, Suyeon, Kim, Hyunkeun, Ko, Kwan Soo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10064660/ https://www.ncbi.nlm.nih.gov/pubmed/37004036 http://dx.doi.org/10.1186/s12929-023-00910-w

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