Cargando…

Safety of Simparica Trio(®) (sarolaner, pyrantel, moxidectin) in heartworm-infected dogs

BACKGROUND: Assessment of the safety of heartworm preventatives in dogs with pre-existing patent heartworm (Dirofilaria immitis) infections is necessary because rapid adult worm and microfilarial death can lead to severe clinical complications, including thromboembolism and anaphylactic shock in dog...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mathur, Sheerin, Malpas, Phyllis B., Mahabir, Sean, Boucher, Joseph, Pullins, Aleah, Gagnon, Genevieve, McTier, Tom L., Maeder, Steven
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10064668/ https://www.ncbi.nlm.nih.gov/pubmed/37004097 http://dx.doi.org/10.1186/s13071-023-05700-9

Ejemplares similares

Efficacy of orally administered combination of moxidectin, sarolaner and pyrantel (Simparica Trio™) for the prevention of experimental Angiostrongylus vasorum infection in dogs
por: Becskei, Csilla, et al.
Publicado: (2020)

Efficacy of a formulation of sarolaner/moxidectin/pyrantel (Simparica Trio(®)) for the prevention of Thelazia callipaeda canine eyeworm infection
por: Bezerra-Santos, Marcos Antonio, et al.
Publicado: (2022)

Laboratory and field studies to investigate the efficacy of a novel, orally administered combination product containing moxidectin, sarolaner and pyrantel for the prevention of heartworm disease (Dirofilaria immitis) in dogs
por: Kryda, Kristina, et al.
Publicado: (2019)

Efficacy of Simparica Trio™, a novel chewable tablet containing sarolaner, moxidectin and pyrantel, against induced hookworm infections in dogs
por: Becskei, Csilla, et al.
Publicado: (2020)

Field safety and efficacy of an orally administered combination of sarolaner, moxidectin and pyrantel (Simparica Trio(®)) for the prevention of angiostrongylosis in dogs presented as veterinary patients
por: Becskei, Csilla, et al.
Publicado: (2020)

Efficacy of a new oral chewable tablet containing sarolaner, moxidectin and pyrantel (Simparica Trio™) against induced ascarid infections in dogs
por: Becskei, Csilla, et al.
Publicado: (2020)

Efficacy of a novel chewable tablet containing sarolaner, moxidectin and pyrantel (Simparica Trio™) against four common tick species infesting dogs in Europe
por: Becskei, Csilla, et al.
Publicado: (2020)

Efficacy of a chewable tablet containing sarolaner, moxidectin, and pyrantel (Simparica Trio(®)) in the treatment of sarcoptic mange caused by Sarcoptes scabiei mite infestations in dogs
por: Becskei, Csilla, et al.
Publicado: (2023)

Efficacy of combination products containing sarolaner, moxidectin and pyrantel (Simparica Trio™) or afoxolaner and milbemycin (NexGard Spectra(®)) against induced infestations of Ixodes holocyclus in dogs
por: Packianathan, Raj, et al.
Publicado: (2020)

Evaluation of the speed of kill of a novel orally administered combination product containing sarolaner, moxidectin and pyrantel (Simparica Trio™) against induced infestations of Ixodes scapularis on dogs
por: Holzmer, Susan, et al.
Publicado: (2020)

Safety and efficacy of a novel oral chewable combination tablet containing sarolaner, moxidectin and pyrantel (Simparica Trio™) against natural flea infestations in client-owned dogs in the USA
por: Kryda, Kristina, et al.
Publicado: (2020)

Efficacy of a novel oral chewable tablet containing sarolaner, moxidectin and pyrantel (Simparica Trio™) against natural flea and tick infestations on dogs presented as veterinary patients in Europe
por: Becskei, Csilla, et al.
Publicado: (2020)

Laboratory studies evaluating the efficacy of a novel orally administered combination product containing sarolaner, moxidectin and pyrantel (Simparica Trio™) for the treatment and control of flea infestations on dogs
por: Kryda, Kristina, et al.
Publicado: (2020)

Preventive efficacy of oral moxidectin at various doses and dosage regimens against macrocyclic lactone-resistant heartworm (Dirofilaria immitis) strains in dogs
por: McTier, Tom L., et al.
Publicado: (2019)

Efficacy of a novel orally administered combination product containing sarolaner, moxidectin and pyrantel (Simparica Trio™) against induced infestations of five common tick species infesting dogs in the USA
por: Kryda, Kristina, et al.
Publicado: (2020)

Insecticidal activity of Simparica and Simparica Trio against Aedes aegypti in dogs
por: Geurden, Thomas, et al.
Publicado: (2023)

Field efficacy and safety of a novel oral chewable tablet containing sarolaner, moxidectin and pyrantel (Simparica Trio™) against naturally acquired gastrointestinal nematode infections in dogs presented as veterinary patients in Europe and the USA
por: Becskei, Csilla, et al.
Publicado: (2020)

Preventive efficacy of six monthly oral doses of Simparica Trio(®), Heartgard(®) Plus, and Interceptor(®) Plus against a macrocyclic lactone-resistant strain (ZoeLA) of heartworm (Dirofilaria immitis) in dogs
por: Myers, Jamie A. E., et al.
Publicado: (2022)

Evaluation of the efficacy of sarolaner (Simparica®) in the prevention of babesiosis in dogs
por: Geurden, Thomas, et al.
Publicado: (2017)

Moxidectin: heartworm disease prevention in dogs in the face of emerging macrocyclic lactone resistance
por: Savadelis, Molly D., et al.
Publicado: (2022)

Successful Removal of Angiostrongylus cantonensis Larvae from the Central Nervous System of Rats 7- and 14-Days Post-Infection Using a Product Containing Moxidectin, Sarolaner and Pyrantel Embonate (Simparica Trio™) in Experimental Infections
por: Henry, Michaela, et al.
Publicado: (2023)

Efficacy of oral moxidectin against susceptible and resistant isolates of Dirofilaria immitis in dogs
por: McTier, Tom L., et al.
Publicado: (2017)

Comparison of the initial and residual speed of Ixodes scapularis kill on dogs treated with a single dose of Bravecto(®) Chew (25 mg/kg fluralaner) or Simparica TRIO(®) (1.2 mg/kg sarolaner, 24 µg/kg moxidectin, 5 mg/kg pyrantel)
por: Reif, Kathryn E., et al.
Publicado: (2023)

Efficacy of sarolaner (Simparica(®)) against induced infestations of Haemaphysalis longicornis on dogs
por: Oda, Kenji, et al.
Publicado: (2019)

Preventive efficacy of four or six monthly oral doses of 24 µg/kg moxidectin compared to six monthly doses of Heartgard® Plus or Interceptor® Plus against macrocyclic lactone-resistant heartworm (Dirofilaria immitis) strains in dogs
por: Kryda, Kristina, et al.
Publicado: (2020)

ProHeart® 12, a moxidectin extended-release injectable formulation for prevention of heartworm (Dirofilaria immitis) disease in dogs in the USA for 12 months
por: McTier, Tom L., et al.
Publicado: (2019)

Comparative speed of kill of sarolaner (Simparica(™)) and fluralaner (Bravecto(®)) against induced infestations of Ctenocephalides felis on dogs
por: Six, Robert H., et al.
Publicado: (2016)

Comparative speed of kill of sarolaner (Simparica(™)) and afoxolaner (NexGard(®)) against induced infestations of Ctenocephalides felis on dogs
por: Six, Robert H., et al.
Publicado: (2016)

Comparative speed of kill of sarolaner (Simparica(™)) and afoxolaner (NexGard(®)) against induced infestations of Amblyomma americanum on dogs
por: Six, Robert H., et al.
Publicado: (2016)

Comparative speed of kill of sarolaner (Simparica(™)) and afoxolaner (NexGard(®)) against induced infestations of Ixodes scapularis on dogs
por: Six, Robert H., et al.
Publicado: (2016)

Comparative speed of kill of sarolaner (Simparica™ Chewables) and fluralaner (Bravecto(®)) against induced infestations of Amblyomma americanum on dogs
por: Six, Robert H., et al.
Publicado: (2016)

Comparative speed of kill of sarolaner (Simparica(®)) and afoxolaner (NexGard(®)) against induced infestations of Ixodes holocyclus on dogs
por: Packianathan, Raj, et al.
Publicado: (2017)

Immediate and persistent efficacy of sarolaner (Simparica™) against Haemaphysalis elliptica on dogs
por: Fourie, Josephus J., et al.
Publicado: (2019)

Comparative speed of kill of sarolaner (Simparica™) and afoxolaner (NexGard®) against induced infestations of Rhipicephalus sanguineus s.l. on dogs
por: Six, Robert H., et al.
Publicado: (2016)

Comparative speed of kill of sarolaner (Simparica(™)) and spinosad plus milbemycin oxime (Trifexis(®)) against induced infestations of Ctenocephalides felis on dogs
por: Six, Robert H., et al.
Publicado: (2016)

Efficacy and safety of sarolaner (Simparica(®)) in the treatment and control of naturally occurring flea infestations in dogs presented as veterinary patients in Australia
por: Packianathan, Raj, et al.
Publicado: (2017)

Comparative speed of kill after treatment with Simparica(™)(sarolaner) and Advantix(®)(imidacloprid + permethrin) against induced infestations of Dermacentor reticulatus on dogs
por: Becskei, Csilla, et al.
Publicado: (2016)

Comparative speed of kill of oral treatments with Simparica(TM)(sarolaner) and Bravecto®(fluralaner) against induced infestations of Rhipicephalus sanguineus on dogs
por: Becskei, Csilla, et al.
Publicado: (2016)

Comparative preventive efficacy of ProHeart(®) 12, Heartgard(®) Plus and Interceptor(®) Plus against a macrocyclic lactone-resistant strain (JYD-34) of heartworm (Dirofilaria immitis) in dogs
por: McTier, Tom L., et al.
Publicado: (2021)

Microfilarial reduction following ProHeart® 6 and ProHeart® SR-12 treatment in dogs experimentally inoculated with a resistant isolate of Dirofilaria immitis
por: McTier, Tom L., et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_dfhkdfds7rl1vi21vj5l6fslv6