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Inducible apelin receptor knockdown reduces differentiation efficiency and contractility of hESC-derived cardiomyocytes

AIMS: The apelin receptor, a G protein-coupled receptor, has emerged as a key regulator of cardiovascular development, physiology, and disease. However, there is a lack of suitable human in vitro models to investigate the apelinergic system in cardiovascular cell types. For the first time we have us...

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Detalles Bibliográficos
Autores principales:	Macrae, Robyn G C, Colzani, Maria T, Williams, Thomas L, Bayraktar, Semih, Kuc, Rhoda E, Pullinger, Anna L, Bernard, William G, Robinson, Emma L, Davenport, Emma E, Maguire, Janet J, Sinha, Sanjay, Davenport, Anthony P
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10064845/ https://www.ncbi.nlm.nih.gov/pubmed/36239923 http://dx.doi.org/10.1093/cvr/cvac065

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