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A rare case of Rosai–Dorfman disease presenting as a pulmonary artery mass in a 33‐year‐old female with hypoxia

Rosai–Dorfman disease (RDD) is a rare form of non‐Langerhans histiocytosis. It is often idiopathic in etiology, but has been associated with viral, autoimmune, and malignant disease. Adequate diagnosis of RDD requires a combination of clinical symptoms, radiography, and histology. Most commonly, pat...

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Detalles Bibliográficos
Autores principales: Dronamraju, Veena, McSurdy, Kaitlyn, Graham, Ryan, Rali, Parth, Kumaran, Maruti, Proca, Daniela, Lashari, Bilal, Toyoda, Yoshiya, Gupta, Rohit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10064855/
https://www.ncbi.nlm.nih.gov/pubmed/37007934
http://dx.doi.org/10.1002/pul2.12214
Descripción
Sumario:Rosai–Dorfman disease (RDD) is a rare form of non‐Langerhans histiocytosis. It is often idiopathic in etiology, but has been associated with viral, autoimmune, and malignant disease. Adequate diagnosis of RDD requires a combination of clinical symptoms, radiography, and histology. Most commonly, patients with RDD present with cervical lymphadenopathy. We describe a case of a young female who was initially thought to have a pulmonary embolism at the time of a COVID‐19 infection but was noted to have a rare occurrence of RDD presenting as a pulmonary artery mass upon further evaluation of radiology and histology. Though RDD is frequently benign, extranodal involvement can progress to end organ damage and must be recognized appropriately.