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IFN-γ Facilitates Corneal Epithelial Cell Pyroptosis Through the JAK2/STAT1 Pathway in Dry Eye

PURPOSE: To investigate the effect of gamma interferon (IFN-γ) on corneal epithelial pyroptosis in an experimental dry eye (DE) model and explore the underlying molecular mechanisms. METHODS: Experimental DE was established in adult wild-type (WT) C57BL/6 mice and Ifng-knockout mice on a C57BL/6 bac...

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Detalles Bibliográficos
Autores principales:	Yang, Xue, Zuo, Xin, Zeng, Hao, Liao, Kai, He, Dalian, Wang, Bowen, Yuan, Jin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2023
Materias:	Cornea
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10064915/ https://www.ncbi.nlm.nih.gov/pubmed/36988949 http://dx.doi.org/10.1167/iovs.64.3.34

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