Sustained Ocular Delivery of Bevacizumab Using Densomeres in Rabbits: Effects on Molecular Integrity and Bioactivity

PURPOSE: To demonstrate that a single administration of an anti-angiogenic monoclonal antibody, when integrated into a novel biodegradable Densomere composed only of the active pharmaceutical ingredient and polymer, maintains molecular integrity, sustained release, and prolonged bioactivity in vitro...

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Detalles Bibliográficos
Autores principales: Peterson, Jan S., Chen, WeiLiam, Libin, Barry M., Boyer, David S., Kaiser, Peter K., Liebmann, Jeffrey M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2023
Materias:
Retina
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10064936/
https://www.ncbi.nlm.nih.gov/pubmed/36976156
http://dx.doi.org/10.1167/tvst.12.3.28

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10064936/
https://www.ncbi.nlm.nih.gov/pubmed/36976156
http://dx.doi.org/10.1167/tvst.12.3.28

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