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Liquen escleroso genital pediátrico en niñas: serie de 11 casos

BACKGROUND: Genital lichen sclerosus decreases the quality of life of women; 10-15% of cases occur in prepubertal girls. METHODS: Retrospective and descriptive study on the characteristics of girls diagnosed with genital lichen sclerosus at the Hospital Universitario de Navarra (Pamplona, Spain) bet...

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Autores principales: Aróstegui, Jorge, Loidi, Leire, Hiltun, Ingrid, Larrea, Mónica, Cascante, Lourdes, Yanguas, Juan Ignacio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Gobierno de Navarra. Departamento de Salud 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10065031/
https://www.ncbi.nlm.nih.gov/pubmed/36408571
http://dx.doi.org/10.23938/ASSN.1014
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author Aróstegui, Jorge
Loidi, Leire
Hiltun, Ingrid
Larrea, Mónica
Cascante, Lourdes
Yanguas, Juan Ignacio
author_facet Aróstegui, Jorge
Loidi, Leire
Hiltun, Ingrid
Larrea, Mónica
Cascante, Lourdes
Yanguas, Juan Ignacio
author_sort Aróstegui, Jorge
collection PubMed
description BACKGROUND: Genital lichen sclerosus decreases the quality of life of women; 10-15% of cases occur in prepubertal girls. METHODS: Retrospective and descriptive study on the characteristics of girls diagnosed with genital lichen sclerosus at the Hospital Universitario de Navarra (Pamplona, Spain) between 2019 and 2022. RESULTS: Eleven girls aged between 4 and 14 year-old were diagnosed. Frequently, diagnostic delays were up to two years after the appearance of the lesions; the girl with a four-year delay showed a significant vulvar architectural alteration. All cases showed the typical sclerotic lesions on the genital area, and two of them also on the back. While six patients were asymptomatic, the rest reported pruritus and/or pain. Treatment with high/very high potency topical corticosteroids achieved a good partial response, without complete remission of the lesions. CONCLUSION: Early diagnosis of genital lichen sclerosus is key to start early treatment, avoiding irreversible genital structural alteration.
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spelling pubmed-100650312023-04-13 Liquen escleroso genital pediátrico en niñas: serie de 11 casos Aróstegui, Jorge Loidi, Leire Hiltun, Ingrid Larrea, Mónica Cascante, Lourdes Yanguas, Juan Ignacio An Sist Sanit Navar Original Breve BACKGROUND: Genital lichen sclerosus decreases the quality of life of women; 10-15% of cases occur in prepubertal girls. METHODS: Retrospective and descriptive study on the characteristics of girls diagnosed with genital lichen sclerosus at the Hospital Universitario de Navarra (Pamplona, Spain) between 2019 and 2022. RESULTS: Eleven girls aged between 4 and 14 year-old were diagnosed. Frequently, diagnostic delays were up to two years after the appearance of the lesions; the girl with a four-year delay showed a significant vulvar architectural alteration. All cases showed the typical sclerotic lesions on the genital area, and two of them also on the back. While six patients were asymptomatic, the rest reported pruritus and/or pain. Treatment with high/very high potency topical corticosteroids achieved a good partial response, without complete remission of the lesions. CONCLUSION: Early diagnosis of genital lichen sclerosus is key to start early treatment, avoiding irreversible genital structural alteration. Gobierno de Navarra. Departamento de Salud 2022-11-18 /pmc/articles/PMC10065031/ /pubmed/36408571 http://dx.doi.org/10.23938/ASSN.1014 Text en https://creativecommons.org/licenses/by-nc/3.0/Este es un artículo publicado en acceso abierto bajo una licencia Creative Commons
spellingShingle Original Breve
Aróstegui, Jorge
Loidi, Leire
Hiltun, Ingrid
Larrea, Mónica
Cascante, Lourdes
Yanguas, Juan Ignacio
Liquen escleroso genital pediátrico en niñas: serie de 11 casos
title Liquen escleroso genital pediátrico en niñas: serie de 11 casos
title_full Liquen escleroso genital pediátrico en niñas: serie de 11 casos
title_fullStr Liquen escleroso genital pediátrico en niñas: serie de 11 casos
title_full_unstemmed Liquen escleroso genital pediátrico en niñas: serie de 11 casos
title_short Liquen escleroso genital pediátrico en niñas: serie de 11 casos
title_sort liquen escleroso genital pediátrico en niñas: serie de 11 casos
topic Original Breve
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10065031/
https://www.ncbi.nlm.nih.gov/pubmed/36408571
http://dx.doi.org/10.23938/ASSN.1014
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