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SARS-CoV-2 is not detectable in cervicovaginal secretions from women with active COVID-19 infection- a pilot study

OBJECTIVE: To detect the shedding of SARS-CoV-2 in cervicovaginal secretions of women with active COVID 19 infection. METHODS: A cross-sectional study from a COVID facility including women aged 20-45 years with active COVID-19 infection, cervicovaginal secretions were collected from cervix and poste...

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Autores principales: Gupta, Pankush, Choudhary, Aashish, Srigyan, Deepankar, Malhotra, Neena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Brazilian Society of Assisted Reproduction 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10065781/
https://www.ncbi.nlm.nih.gov/pubmed/34995047
http://dx.doi.org/10.5935/1518-0557.20210103
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author Gupta, Pankush
Choudhary, Aashish
Srigyan, Deepankar
Malhotra, Neena
author_facet Gupta, Pankush
Choudhary, Aashish
Srigyan, Deepankar
Malhotra, Neena
author_sort Gupta, Pankush
collection PubMed
description OBJECTIVE: To detect the shedding of SARS-CoV-2 in cervicovaginal secretions of women with active COVID 19 infection. METHODS: A cross-sectional study from a COVID facility including women aged 20-45 years with active COVID-19 infection, cervicovaginal secretions were collected from cervix and posterior fornix using dacron swab within 7 days of symptom onset or 5 days of nasopharyngeal rRT-PCR test positivity in asymptomatic women. Cervicovaginal samples of women with mild symptoms were tested using rRT-PCR for SARS-CoV-2. RESULTS: SARS-CoV-2 was not detected in cervicovaginal secretions of any of the 11 women included in the study. CONCLUSIONS: SARS-CoV-2 does not shed in the cervicovaginal secretions of women with mild COVID 19 infection, ruling out sexual and vertical transmission of virus in mild and asymptomatic disease.
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spelling pubmed-100657812023-04-01 SARS-CoV-2 is not detectable in cervicovaginal secretions from women with active COVID-19 infection- a pilot study Gupta, Pankush Choudhary, Aashish Srigyan, Deepankar Malhotra, Neena JBRA Assist Reprod Original Article OBJECTIVE: To detect the shedding of SARS-CoV-2 in cervicovaginal secretions of women with active COVID 19 infection. METHODS: A cross-sectional study from a COVID facility including women aged 20-45 years with active COVID-19 infection, cervicovaginal secretions were collected from cervix and posterior fornix using dacron swab within 7 days of symptom onset or 5 days of nasopharyngeal rRT-PCR test positivity in asymptomatic women. Cervicovaginal samples of women with mild symptoms were tested using rRT-PCR for SARS-CoV-2. RESULTS: SARS-CoV-2 was not detected in cervicovaginal secretions of any of the 11 women included in the study. CONCLUSIONS: SARS-CoV-2 does not shed in the cervicovaginal secretions of women with mild COVID 19 infection, ruling out sexual and vertical transmission of virus in mild and asymptomatic disease. Brazilian Society of Assisted Reproduction 2023 /pmc/articles/PMC10065781/ /pubmed/34995047 http://dx.doi.org/10.5935/1518-0557.20210103 Text en https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Gupta, Pankush
Choudhary, Aashish
Srigyan, Deepankar
Malhotra, Neena
SARS-CoV-2 is not detectable in cervicovaginal secretions from women with active COVID-19 infection- a pilot study
title SARS-CoV-2 is not detectable in cervicovaginal secretions from women with active COVID-19 infection- a pilot study
title_full SARS-CoV-2 is not detectable in cervicovaginal secretions from women with active COVID-19 infection- a pilot study
title_fullStr SARS-CoV-2 is not detectable in cervicovaginal secretions from women with active COVID-19 infection- a pilot study
title_full_unstemmed SARS-CoV-2 is not detectable in cervicovaginal secretions from women with active COVID-19 infection- a pilot study
title_short SARS-CoV-2 is not detectable in cervicovaginal secretions from women with active COVID-19 infection- a pilot study
title_sort sars-cov-2 is not detectable in cervicovaginal secretions from women with active covid-19 infection- a pilot study
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10065781/
https://www.ncbi.nlm.nih.gov/pubmed/34995047
http://dx.doi.org/10.5935/1518-0557.20210103
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