Actin-regulated Siglec-1 nanoclustering influences HIV-1 capture and virus-containing compartment formation in dendritic cells

The immunoglobulin-like lectin receptor CD169 (Siglec-1) mediates the capture of HIV-1 by activated dendritic cells (DCs) through binding to sialylated ligands. These interactions result in a more efficient virus capture as compared to resting DCs, although the underlying mechanisms are poorly under...

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Detalles Bibliográficos
Autores principales: Gutiérrez-Martínez, Enric, Benet Garrabé, Susana, Mateos, Nicolas, Erkizia, Itziar, Nieto-Garai, Jon Ander, Lorizate, Maier, Borgman, Kyra JE, Manzo, Carlo, Campelo, Felix, Izquierdo-Useros, Nuria, Martinez-Picado, Javier, Garcia-Parajo, Maria F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10065798/
https://www.ncbi.nlm.nih.gov/pubmed/36940134
http://dx.doi.org/10.7554/eLife.78836

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10065798/
https://www.ncbi.nlm.nih.gov/pubmed/36940134
http://dx.doi.org/10.7554/eLife.78836

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