A case report of a prolonged decrease in tacrolimus clearance due to co-administration of nirmatrelvir/ritonavir in a lung transplant recipient receiving itraconazole prophylaxis

BACKGROUND: Drug-drug interaction management is complex. Nirmatrelvir/ritonavir is a potent cytochrome P450 (CYP) 3A inhibitor and influences pharmacokinetics of co-administered drugs. Although there are several reports about drug-drug interactions of nirmatrelvir/ritonavir, an influence of a concom...

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Detalles Bibliográficos
Autores principales: Tsuzawa, Ayumi, Katada, Yoshiki, Umemura, Keisuke, Sugimoto, Mitsuhiro, Nishikawa, Asami, Sato, Yu-ki, Yoshida, Yuko, Kitada, Noriaki, Yonezawa, Atsushi, Nakajima, Daisuke, Date, Hiroshi, Terada, Tomohiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10066007/
https://www.ncbi.nlm.nih.gov/pubmed/37004119
http://dx.doi.org/10.1186/s40780-023-00280-3

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