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Molecular mechanism on forcible ejection of ATPase inhibitory factor 1 from mitochondrial ATP synthase

IF(1) is a natural inhibitor protein for mitochondrial F(o)F(1) ATP synthase that blocks catalysis and rotation of the F(1) by deeply inserting its N-terminal helices into F(1). A unique feature of IF(1) is condition-dependent inhibition; although IF(1) inhibits ATP hydrolysis by F(1), IF(1) inhibit...

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Detalles Bibliográficos
Autores principales: Kobayashi, Ryohei, Ueno, Hiroshi, Okazaki, Kei-ichi, Noji, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10066207/
https://www.ncbi.nlm.nih.gov/pubmed/37002198
http://dx.doi.org/10.1038/s41467-023-37182-9

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